Peritumoral Edema in Resected Meningiomas: Study of Factors Associated with the Variability of Postoperative Duration

Arévalo-Sáenz A, Rascón Ramírez FJ , Ferrandez-Pujante Band Sánchez MP

Department of Neurosurgery, Clinical Hospital San Carlos, Spain Department of Neurosurgery, La Zarzuela University Hospital, Spain

^*Correspondance to: Alejandra Arévalo Sáenz 

 PDF  Full Text DOI: 10.25107/2474-1647.3679

Abstract

Background: It is well known that edema can persist after meningioma resection, and sometimes it is not resolved after this time. This study aimed to establish the relationship between a series of variables associated with meningioma or surgery, and the duration of postoperative edema. Methods: We conducted a retrospective study of 77 meningiomas resected at our institution between January 2016 and January 2018 with a maximum follow-up period of up to three years. The independent variables collected were demographics, tumor location, relationship with the sinuses (invasion/contact), relationship with arterial structures, deviation from the midline, volume (cm3 ), degree of initial edema, WHO histological classification, degree of atypia, degree of resection, previous embolization, and development of complications. The edema levels were classified according to the classification described by Ide et al.: GR0, GR1, and GR2. Measurements were performed using FLAIR magnetic resonance sequences. Statistical analyses were performed using the SPSS 21. Results: Age (p=0.003), deviation from the midline (p=0.001), and tumor volume (p<0.001) were correlated with outcome using Spearman's test. Univariate analysis revealed that the localization (p=0.016), initial edema (p<0.001), degree of atypia (p=0.019), and presence of previous embolization (p=0.037) were statistically significant. In multivariate analysis, only age, initial edema, and embolization were significant independent predictors. Conclusion: These results suggest that the degree of initial edema, midline deviation, tumor volume, tumor location, degree of atypia, and previous embolization may be important predictors of postoperative edema duration.

Keywords

Meningioma; Microsurgery; Peritumoral edema; Postoperative edema; Size tumoral

Cite the article

Arévalo-Sáenz A, Rascón Ramírez FJ, Ferrandez-Pujante B, Sánchez MP. Peritumoral Edema in Resected Meningiomas: Study of Factors Associated with the Variability of Postoperative Duration. Clin Surg. 2023; 8: 3679..