Evaluation of a Probabilistic Antibiotherapy Protocol for Community Osteoarticular Infections in Children

Bourgoin A1 , Common H1 , Arvieux C2 , Marleix S1 , Lucas G1 , Fraisse B1 , Jeantet R-E1 , JolivetGougeon A3 , Tattevin P2 and Violas P1*

1 Department of Pediatric Surgery, CHU de Rennes, France 2 Infectious Diseases and Medical Resuscitation, CHU de Rennes, France 3 University of Rennes 1, INSERM, CHU Rennes Laboratoire de Bact?riologie, Institut NUMECAN, France

^*Correspondance to: Violas P 

 PDF  Full Text DOI: 10.25107/2474-1647.3008

Abstract

Objective: To evaluate a protocol of empirical intravenous antibacterial treatment amoxicillinclavulanate (age 2 years) for Bone and Joint Infections (BJI) in children. Patients and Methods: Retrospective observational study in a referral center for complicated BJI. Data collected through medical files, and contact with parent(s)/general practitioner for one yearfollow-up. Results: From 2011 to 2014, 63 children have been admitted for community-acquired acute BJI (mean age, 5.2+4.3 years): Arthritis (n=42), osteomyelitis (n=14) or osteoarthritis (n=7), mainly involving the knee (n=22), the hip (n=21) or the ankle (n=10), mostly due to Staphylococcus aureus (n=14) and Kingella kingae (n=9). All children were cured at one-year follow-up, with a mean hospital stay duration of 5.0 ? 2.4 days, a change of antibacterial treatment outside of the protocol in 11 cases (16%), and secondary surgery in 9 cases (11.5%). Conclusion: The protocol is well adapted to community-acquired BJI in our population

Keywords

Osteoarticular infections; Antibiotic; Empirical; Kingella kingae; Staphylococcus aureu

Cite the article

Bourgoin A, Common H, Arvieux C, Marleix S, Lucas G, Fraisse B, et al. Evaluation of a Probabilistic Antibiotherapy Protocol for Community Osteoarticular Infections in Children. Clin Surg. 2020; 5: 3008.