Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Bariatric Surgery
  •  Oral and Maxillofacial Surgery
  •  Minimally Invasive Surgery
  •  Otolaryngology - Head and Neck Surgery
  •  Emergency Surgery
  •  Urology
  •  Neurological Surgery
  •  Colon and Rectal Surgery

Abstract

Citation: Clin Surg. 2023;8(1):3672.Research Article | Open Access

Periprocedural Risk Predictors and Body Mass Index Impact Long-Term Prognosis in Patients Undergoing Coronary Artery Bypass Grafting

Dokollari A, Sicouri S, Kjelstrom S, Montone G, Cameli M, Yoshi Y, Gemelli M, Hassanabad AF, Ghorpade N, Cabrucci F, Bacchi B, Bonacchi M, Ramlawi B, Wertan MA and Sutter FP

1Department of Cardiac Surgery Research, Lankenau Institute for Medical Research, Main Line Health, Wynnewood, Pennsylvania, USA Department of Cardiac Surgery, Lankenau Heart Institute, Lankenau Medical Center, Main Line Health, Wynnewood, Pennsylvania, USA Main Line Health Center for Population Health Research, Lankenau Institute for Medical Research, Wynnewood, Pennsylvania, USA Department of Cardiology, University of Siena, Italy Department of Cardiac Surgery, University of Padua, Italy Department of Cardiac Surgery, Cumming School for Medical Research; University of Calgary, Canada Department of Cardiac Surgery, St. Boniface Hospital, University of Manitoba, Winnipeg, Canada 8Department of Clinical and Experimental, University of Florence, Florence, Italy

*Correspondance to: Aleksander Dokollari 

 PDF  Full Text DOI: 10.25107/2474-1647.3672

Abstract

Objective: The main goal of this study is to identify risk predictors for all-cause mortality in patients undergoing Coronary Artery Bypass Grafting (CABG) based on Body Mass Index (BMI). Methods: All consecutive 4,871 patients undergoing isolated CABG between 2005 and 2021, were included in the study. Underweight (<19 kg/m2) (n=42), normal/obese (BMI= 19-39.9 kg/m2) (n=4,622), and morbidly obese (BMI ≥ 40 kg/m2) (n=215) patients were compared for preoperative characteristics. A propensity-adjusted analysis was used to compare the groups. Primary outcome were long-term incidence of death and Major Adverse Cardiovascular and Cerebrovascular Events (MACCE). Results: Preoperatively, mean age was 71.2 (normal/obese), vs. 75.5 (underweight) vs. 65.9 (morbidly obese) years old. Intraoperatively, morbidly obese patients had higher operating room time. Postoperatively, morbidly obese, and underweight patients had higher blood product transfusion and 30-day readmission rate. Primary outcome of all-cause mortality was normal/obese 528/4622 (11.3%) vs. underweight 11/42 (26.2%) vs. morbidly obese 32/215 (14.9%), p=0.003. MACCE was significantly higher in morbidly obese patients 17/215 (7.9%), p=0.024. Predictors for all-cause mortality in morbidly obese patients were non-white patients, diabetes, Peripheral Vascular Disease (PVD), STS ≥ 4%, dialysis, hypertension, Chronic Obstructive Pulmonary Disease (COPD), Ejection Fraction (EF) <50%, and Atrial fibrillation (Afib). Predictors for all-cause mortality in underweight patients were male gender, white race, STS ≥ 4%, dialysis, EF<50%, and hypertension. Conclusion: Death rate in underweight patients was two-fold compared to normal/obese patients and 57% higher compared to morbidly obese patients. MACCE rate was significantly higher in morbidly obese patients.

Keywords

Obesity; BMI; Underweight; CABG; Risk Factors: Long-Term Prognosis

Cite the article

Dokollari A, Sicouri S, Kjelstrom S, Montone G, Cameli M, Yoshi Y, et al. Periprocedural Risk Predictors and Body Mass Index Impact Long-Term Prognosis in Patients Undergoing Coronary Artery Bypass Grafting. Clin Surg. 2023; 8: 3672..

Search Our Journal

Journal Indexed In

Articles in PubMed

Mesh Sprayer Device with Liquefied Mesh Delivery System: Proposed Alternative for Currently Available Meshes in Hernia Repair and Supplement to Abdominal Closure
 PubMed  PMC  PDF  Full Text
Automated Sagittal Craniosynostosis Classification from CT Images Using Transfer Learning
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Melatonin Attenuates Ischemia/Reperfusion Injury of Rat Flap through the Rip3-Mlkl-Mptp Necroptotic Pathway
 Abstract  PDF  Full Text
Mouth Opening Retaining Appliance after Coronoidotomy for the Treatment of Trismus: Effects on Pain during Postoperative Training and Maximal Extent of Mouth Opening
 Abstract  PDF  Full Text
View More...