Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Oral and Maxillofacial Surgery
  •  Transplant Surgery
  •  Plastic Surgery
  •  Obstetrics Surgery
  •  Urology
  •  Breast Surgery
  •  Ophthalmic Surgery
  •  Surgical Oncology


Citation: Clin Surg. 2020;5(1):2763.Research Article | Open Access

Severe Hematuria in the Recurrent Benign Hyperplastic Prostate: Underlying Pathology

Xin Jun Wang, Xiao Lu Zhu, Pei Ming Bai and Guang Cheng Luo*

Department of Urology, Zhongshan Hospital Xiamen University, China

*Correspondance to: Guang Cheng Luo 

 PDF  Full Text DOI: 10.25107/2474-1647.2763


Objective: To investigate the underlying morphology and pathology of severe hematuria in recurrent prostatic hyperplasia. Methods: We reviewed records for 801 primary BPH patients and 57 recurrent BPH patients. We collected prostate tissues from 29 patients who accepted TURP twice for BPH and collected intraoperative images to compare the proportion of the prostatic epithelium, glandular lumen, smooth muscle and micro-vessel density between primary and recurrent BPH tissues. Results: Severe hematuria is the main reason for hospitalization in patients with recurrent BPH, accounting for approximately 45.61%. In the primary BPH group, the average proportions of the prostatic epithelium, glandular lumen, and smooth muscle were 18.4% ± 13.2%, 9.3% ± 3.5%, and 35.7% ± 15.2%, respectively, and the average proportions of those in the recurrent BPH group were 16.4% ± 8.5%, 8.6% ± 3.3%, and 29.7% ± 12.2%. The proportion of smooth muscle was lower than that of the primary BPH group (P<0.05). The MVD value was higher in the recurrent BPH group than in the primary BPH group (27.5 ± 9.3) (P<0.05). Conclusion: The general appearance of the recurrent hyperplastic prostate was irregular nodular hyperplasia, and the surface bled easily. Recurrent hyperplastic adenomas with a higher MVD and thinner blood vessel walls may also be more likely to bleed.


Prostatic hyperplasia; Recurrence; Hematuria; Pathology; Immunohistochemistry

Cite the article

Wang XJ, Zhu XL, Bai PM, Luo GC. Severe Hematuria in the Recurrent Benign Hyperplastic Prostate: Underlying Pathology. Clin Surg. 2020; 5: 2763..

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