Preoperative Diagnosis of Papillary Carcinoma Arising from Thyroglossal Duct Cyst: Two Case Reports and Literature Review

Reo Miura*, Atsuo Ikeda, Kazuhiro Nakamura, Masato Morita, Hirotaka Suzuki, Hiroumi Matsuzaki and Takeshi Oshima

Department of Otolaryngology and Head and Neck Surgery, Nihon University School of Medicine, Japan

^*Correspondance to: Reo Miura 

 PDF  Full Text DOI: 10.25107/2474-1647.2739

Abstract

Thyroglossal Duct Cyst (TGDC) is a common disease that rarely develops into carcinoma. We report two cases of papillary carcinoma arising from TGDC diagnosed preoperatively. Case 1: A 36-year-old woman presented with a painless mass in the midline of the neck. Computed Tomography (CT) showed an 18 mm mass lesion in the area surrounded by the hyoid bone and thyroid cartilage and bilateral cervical lymph node enlargements. The pathological findings were papillary carcinoma with bilateral lymph node metastases. Case 2: A 44-year-old woman presented with a painless mass in the midline of the neck. CT showed a cystic lesion with a 37 mm calcification and a partial contrast effect in the middle of the hyoid bone. The pathological findings were papillary carcinoma without lymph node metastases. Both lesions were definitively diagnosed by Fine Needle Aspiration (FNA). Both patients were followed up without adjuvant therapy and had good courses without recurrence at 31 and 29 months after surgery. The possibility of thyroglossal duct cancer should be kept in mind if preoperative imaging shows findings that are not typical of TGDC, such as thickening or irregularities of the cyst wall or solid lesions within the cyst and calcification. Preoperative ultrasound-guided FNA is effective for developing an appropriate surgical plan if we suspect malignancy.

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Cite the article

Miura R, Ikeda A, Nakamura K, Morita M, Suzuki H, Matsuzaki H, et al. Preoperative Diagnosis of Papillary Carcinoma Arising from Thyroglossal Duct Cyst: Two Case Reports and Literature Review. Clin Surg. 2020; 5: 2739..