
Journal Basic Info
- Impact Factor: 2.395**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Neurological Surgery
- Otolaryngology - Head and Neck Surgery
- Pediatric Surgery
- Orthopaedic Surgery
- Cardiovascular Surgery
- General Surgery
- Thoracic Surgery
- Plastic Surgery
Abstract
Citation: Clin Surg. 2020;5(1):2708.Research Article | Open Access
Factors Affecting HCC Recurrence Post Liver Resection versus Living Transplantation
Morsi Mohamed1, Wael Mansy1*, Sayed Elhendawey2, Mohamed Basyouny3 and karim Boudjema4
1Hepato-Pancreatico-Biliary Surgery Department, Zagazig University, Egypt
2General Surgery Department, Zagazig University Hospital, Egypt
3FRCS, Liver Transplant Unit, Maadi Armed Forces Medical Compound, Egypt
4Liver Transplant and Hepatobiliary Surgery Department, Rennes University, France
*Correspondance to: Wael Mansy
PDF Full Text DOI: 10.25107/2474-1647.2708
Abstract
Background: Liver resection, liver transplantation and loco-regional ablation (Radiofrequency Ablation (RFA), Microwave Ablation (MWA) and Trans-Arterial Chemo-Embolization (TACE)) are the optimal ways of HCC management. The optimal treatment for HCC has long been debated according to patient condition. Patients and Methods: A retrospective study from January 2012 till March 2019 on 118 patients with HCC (58 patients underwent Hepatic Resection (HR) and 58 patients underwent LDLT). Results: There was no significant difference between the HR group and LDLT group regarding the overall survival and disease-free survival. Overall survival at 1, 3 and 5 yrs. was 94.9%, 78% and 74.5% in LDLT group while was 89.83%, 71.19% and 62.71% in HR group respectively. Disease free survival at 1, 3 and 5yrs. was 88.1%, 62.7% and 61.01% in LDLT group while was 83.05%, 57.63% and 50.85% in HR respectively. Conclusion: In management of early stage HCC HR should be considered an alternative to LDLT. The most important factors affecting HCC recurrence were tumor behavior and preoperative AFP.
Keywords
Hepatic resection; Living donor liver transplant; Hepatocellular carcinoma; Recurrence
Cite the article
Mohamed M, Mansy W, Elhendawey S, Basyouny M, Boudjema K. Factors Affecting HCC Recurrence Post Liver Resection versus Living Transplantation. Clin Surg. 2020; 5: 2708..