Quantitative Evaluation of Subzygomatic Depression Secondary to Single Longitudinal Masseter Hypertrophy with Botulinum Toxin A Injection Using Three-dimensional Scanning Technique

Zhang S1,2#, Zhang X1,2#, Chen X1,2, Luo S1,2* and Hao L1,2*

1The Plastic and Aesthetic Center, The First Affiliated Hospital of Harbin Medical University, P. R. China
2NHC Key Laboratory of Cell Transplantation, Harbin Medical University, P.R. China
#These authors contributed equally to this work

^*Correspondance to: Sai Luo 

 PDF  Full Text DOI: 10.25107/2474-1647.3619

Abstract

Background: Botulinum Toxin-A (BTX-A) injection for masseter hypertrophy may induce decreases in soft tissue bulging degree in the subzygomatic area (subzygomatic depression). This study aimed to investigate the efficacy of Three-Dimensional (3D) scanning technology as a quantitative method to evaluate this complication. Materials and Methods: Between July 2019 and December 2021, imaging data of patients (aged 18 to 45 years) who received BTX-A injection for single longitudinal masseter hypertrophy were retrospectively analyzed. Changes in the soft tissue bulging degree in the masseter muscle area and subzygomatic area, assessed using Artec EVA 3D scanner, before and 2 and 6 months after surgery were quantitatively analyzed and expressed by linear and surface distance. Statistical analysis was performed on this 3D data. Results: Between July 2019 and December 2021, 91 patients with single longitudinal masseter hypertrophy were included in the study according to the exclusion criteria and received BTX-A injection. Compared with preoperative values, a statistically significant decrease was noted in the curve line in the subzygomatic area 2 months after the operation (P<0.05), with no statistical difference between the preoperative and 6-month postoperative values (P>0.05). Most patients experienced a decrease in the bulging degree of the soft tissue in the subzygomatic and masseter muscle areas at 2 months postoperatively, and some patients maintained the effect at 6 months after surgery. Conclusion: BTX-A injection could induce subzygomatic area depression to different extents during treatment of single longitudinal masseter hypertrophy, and 3D scanning technology was an accurate and intuitive way to present reliable data.

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Cite the article

Zhang S, Zhang X, Chen X, Luo S, Hao L. Quantitative Evaluation of Subzygomatic Depression Secondary to Single Longitudinal Masseter Hypertrophy with Botulinum Toxin A Injection Using Three-dimensional Scanning Technique. Clin Surg. 2023; 8: 3619..