Efficacy and Safety of Integrative and Complementary Therapy (ICT) based on Cucurbita Maxima in the Treatment of Patients with Overactive Bladder: A Multicentre Prospective Observational Study

Michele Carlo Schiavi1 , Paolo Luffarelli2*, Franca Natale3 , Stefania Cappello4 , Antonella Paolucci5 , Cosimo Oliva5 , Pier Luigi Palazzetti1 , Anna Di Pinto6 and Marzio Angelo Zullo2

1 Department of Gynaecological and Obstetric Sandro Pertini Hospital, Rome, Italy 2 Department of Surgery-Week Surgery, Campus Bio medico, University of Rome, Rome, Italy 3 Department of Gynaecology, San Carlo di Nancy Hospital, Rome, Italy 4 Nuova Villa Claudia, Rome, Italy 5 Woman prevention centre, Terni, Italy 6 Department of Gynaecological and Obstetric, San Filippo Neri Hospital, Rome, Italy 7 Sapienza University of Rome, Rome, Italy

^*Correspondance to: Paolo Luffarelli 

 PDF  Full Text DOI: 10.25107/2474-1647.3018

Abstract

Objective: The aim of this study was to assess the effectiveness and safety of an Integrative Complementary Therapy (ICT) based on cucurbita maxima in the improvement of Overactive Bladder (OAB) symptoms in women. Materials and Methods: Two hundred thirty-eight patients received ICT two tablet orally/daily for 12 weeks. Primary endpoint was changes in the total number of voids/24 h, urgent micturition?s/24 h, urinary incontinence events/24 h, nocturia events after 12 weeks of treatment. Secondary endpoints included the assessment of the quality of life through the use of the OAB-Q symptom and HRQL scale, UDI-6 and SF-36 questionnaires. The satisfaction was evaluated by PGI-I. Results: After 12-weeks the reduction in the mean number of voids (9.87 ? 2.45 vs. 7.63 ? 1.22, p=0.01), urgent micturition (4.71 ? 1.28 vs. 2.53 ? 1.22, p

Keywords

Complementary medicine; Cucurbita maxima; Overactive bladder; Quality of life; Resveratrol; urge urinary incontinence

Cite the article

Schiavi MC, Luffarelli P, Natale F, Cappello S, Paolucci A, Oliva C, et al. Eff cacy and Safety of Integrative and Complementary Therapy (ICT) based on Cucurbita Maxima in the Treatment of Patients with Overactive Bladder: A Multicentre Prospective Observational Study. Clin Surg. 2020; 5: 3018..