Short Warm Ischemic Time Prevents Early Allograft Dysfunction in Deceased Donor Liver Transplantation

Jong Man Kim1 , Jongwook Oh2 , Jinsoo Rhu1 , Gyu-Seong Choi1 and Jae-Won Joh1*

1 Department of Surgery, Samsung Medical Center, Sungkyunkwan University, School of Medicine, Republic of Korea 2 Department of Surgery, Samsung Changwon Hospital, Sungkyunkwan University, School of Medicine, Republic of Korea

^*Correspondance to: Jae-Won Joh 

 PDF  Full Text DOI: 10.25107/2474-1647.2951

Abstract

Early Allograft Dysfunction (EAD) is a severe complication that may arise after liver transplantation, and the factors related to EAD have not been established. The aim of this study was to investigate the risk factors and survival time associated with EAD after Deceased Donor Liver Transplantation (DDLT). This was a retrospective cohort study that included the data from 265 adult patients who underwent their first DDLT between April 2003 March 2017. Twenty-three patients (8.7%) developed EAD. The cumulative overall survival rates at 1, 3, and 5 years were 81.4%, 76.2%, and 74.2%, respectively, in the non-EAD group and 52.2%, 52.2%, and 44.7% in the EAD group (P35 min predicted development of EAD. Rapid revascularization to minimize WIT prevented development of EAD in patients with high MELD score after DDLT.

Keywords

Liver transplantation; Ischemic time; Reperfusion

Cite the article

Kim JM, Oh J, Rhu J, Choi G-S, Joh J-W. Short Warm Ischemic Time Prevents Early Allograft Dysfunction in Deceased Donor Liver Transplantation. Clin Surg. 2020; 5: 2951..