Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Plastic Surgery
  •  Robotic Surgery
  •  Surgical Oncology
  •  Colon and Rectal Surgery
  •  Obstetrics Surgery
  •  Gynecological Surgery
  •  Emergency Surgery
  •  Urology


Citation: Clin Surg. 2018;3(1):2163.Research Article | Open Access

The Use of a Cellular Dermal Matrix (ADM) in Prepectoral Implant-Based Breast Reconstruction: A Review of the Literature

Mackenzie A, Kasem A and Mokbel K

Department of General Surgery, Medway Maritime Hospital, UK
Department of Breast and Oncoplastic Surgery, The Princess Grace Hospital, UK
Department of Breast and Oncoplastic Surgery, The Princess Royal University Hospital, UK

*Correspondance to: Aliya Mackenzie 

 PDF  Full Text DOI: 10.25107/2474-1647.2163


Background/Aims: Prepectoral implant-based breast reconstruction with the use of Acellular Dermal Matrix (ADM) has re-emerged as an increasingly popular choice for post-mastectomy breast reconstruction. However, controversy remains regarding complication rates, cosmetic outcomes and patient selection.Materials and
This review examines the current literature regarding ADM and prepectoralbased breast reconstruction; highlighting technique, complication rates, cosmetic outcome, patient safety and satisfaction, appropriate patient selection, and areas for further research.Results: This appraisal clearly demonstrates that pre-pectoral breast reconstruction is safe, feasible and has excellent short-term outcomes (cosmesis, complication rates and patient satisfaction). Main advantages include decreased animation deformity, shoulder dysfunction and chronic pain, and possibly a lower incidence of capsular contracture. Notable shortcomings include small population size and lack of long-term follow-up regarding oncological and aesthetic outcomes especially the incidence of rippling. Outcomes establish dependency on patient factors (i.e. BMI, co-morbidities, lifestyle, etc.), breast size, intra-operative flap assessment, and adjuvant radiotherapy. Recent evidence suggests that post mastectomy radiation does not represent a contraindication to this approach. Meshed ADMs seem to be superior to solid ADMs in terms of integration and cost effectiveness.Conclusion: Short-term outcomes of pre-pectoral ADM-assisted implant-breast breast reconstruction of are promising; however, long-term outcomes are yet to be assessed, requiring further research.


Pre-pectoral; Mastectomy; Breast cancer; ADM; Acellular dermal matrix

Cite the article

Mackenzie A, Kasem A, Mokbel K. The Use of a Cellular Dermal Matrix (ADM) in Pre-pectoral Implant-Based Breast Reconstruction: A Review of the Literature. Clin Surg. 2018; 3: 2163.

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