Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Pediatric Surgery
  •  Oral and Maxillofacial Surgery
  •  Emergency Surgery
  •  Colon and Rectal Surgery
  •  General Surgery
  •  Neurological Surgery
  •  Robotic Surgery
  •  Surgical Oncology

Abstract

Citation: Clin Surg. 2019;4(1):2611.Research Article | Open Access

A Comparison of a Laparoscopic Kidney Transplantation Technique and an Open Approach in a Pig Model

Bulang He, Gabrielle C Musk, Zi Qin Ng, Lingjun Mou, Helen Kershaw, Mark Newman, Rajalingam Sinniah and Jeffrey M Hamdorf AM

Department of Surgery, The University of Western Australia, Australia
The University of Western Australia, Australia
Department of Surgery, Sir Charles Gairdner Hospital, Australia
Department of Surgery, Murdoch University, Australia
Department of Histopathology, Fiona Stanley Health Campus, Australia

*Correspondance to: Bulang He 

 PDF  Full Text DOI: 10.25107/2474-1647.2611

Abstract

Introduction: The expansion of laparoscopic surgery has emerged in the field of kidney transplantation as it confers multiple benefits. The aim of this study was to compare the outcomes of kidney transplantation by laparoscopic surgery versus open surgery in a pig model. Materials and Methods: Sixteen large white pigs were included in this study. Ten pigs underwent laparoscopic kidney transplantation (Lap Group) and 6 pigs had open kidney transplantation (Open Group). Cooling of the kidney graft was introduced during vessel anastomosis. The time for vessel anastomosis was recorded. The kidney graft temperature and body temperature were monitored. Blood samples and biopsy of kidney graft were taken for analysis of kidney function. Results: All surgeries were performed successfully. The time for renal artery anastomosis was longer in the Lap Group while the time for renal vein and ureter anastomosis was similar in both groups. The increase in kidney graft temperature was 3.6°C less in the Open Group than in the Lap Group. The creatinine level was similar at all time points and there was no difference in histopathology between two groups. Conclusion: The kidney transplantation by laparoscopic surgery is safe and feasible. The kidney graft function was comparable in two groups. The laparoscopic technique has revealed a possible consideration for application to human orthotopic kidney transplantation in the future.

Keywords

Laparoscopy; Kidney graft; Kidney transplantation

Cite the article

He B, Musk GC, Ng ZQ, Mou L, Kershaw H, Newman M, et al. A Comparison of a Laparoscopic Kidney Transplantation Technique and an Open Approach in a Pig Model. Clin Surg. 2019; 4: 2611.

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