The Role of Fibrin Tissue Sealant in Groin Dissection to Reduce Seroma Formation: A Prospective Study

MD Ray, Ashutosh Mishra, Mahesh Sultania and Pankaj Kumar Garg

Department of Surgical Oncology, BRAIRCH, AIIMS, India
Department of Surgical Oncology, AIIMS, India
Department of surgery, UCMS & GTB hospital, India

^*Correspondance to: Ashutosh Mishra 

 PDF  Full Text DOI: 10.25107/2474-1647.1961

Abstract

Background: Prolong wound drainage and seroma formation has been classically associated with groin dissection affecting the quality of life of patients adversely. Recently, there has been growing interest in use of tissue sealants to reduce prolonged wound drainage and seroma formation.Method: The present study was designed to evaluate the role of tissue sealant following groin dissection in reducing wound drainage and seroma formation. All the patients of age of 18-years and above undergoing groin dissection for various indications were included in the study as cases. Controls were recruited in the study from the computerized database of the patients. After completion of groin dissection and before the surgical wound closure, fibrin tissue sealant was applied in droplets locally in the groin wound in the cases.Result: The prospective study involved 40 patients and evaluated 52 groin dissections. The cases and controls were comparable for age, gender, body mass index, Diabetes mellitus, and number of lymph bodes harvested. There was no statistically significant difference between the two groups with respect to median time (in days) required for drain removal (11 vs. 14, p value 0.75), number of clinically evident seroma formation (8 vs. 7, p value 0.76), frequency of surgical site infection or flap necrosis.
Conclusion: Fibrin tissue sealants are unlikely to decrease the wound drainage or number of clinically evident seromas following groin dissection.

Keywords

Groin dissection: Lymphadenectomy; Seroma; Tissue sealant; Morbidity

Cite the article

Ray MD, Mishra A, Sultania M, Garg PK. The Role of Fibrin Tissue Sealant in Groin Dissection to Reduce Seroma Formation: A Prospective Study. Clin Surg. 2018; 3: 1961.