Necrotizing Pancreatitis: Advances in Management

Sarah A Moore, Ryan P. Dumas and Carrie A Sims

Department of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Department of Surgery, Division of Traumatology, Surgical Critical Care & Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

^*Correspondance to: Sarah A Moore 

 PDF  Full Text DOI: 10.25107/2474-1647.1437

Abstract

Acute pancreatitis is a common disease process that results in significant morbidity and mortality. While the disease course may be mild and self-limited, 15%-25% of patients develop necrotizing pancreatitis, which may become secondarily infected. The use of standardized scoring systems and clinical classification schemes has allowed multicenter trials to evaluate the management of necrotizing pancreatitis and have greatly improved outcomes. Supportive care with fluid resuscitation, nutrition, and appropriate use of antibiotics are the mainstays of early management. Once fluid collections have progressed to walled-off necrosis, catheter-based drainage is generally sufficient, with few patients requiring surgical intervention. Complications of necrotizing pancreatitis include mesenteric venous thrombosis, abdominal compartment syndrome, bowel perforation, and hemorrhage. Further understanding the appropriate timing of interventions may potentially lead to fewer complications, decreased length of hospitalization, and improved outcomes.

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Cite the article

Moore SA, Dumas RP, Sims CA. Necrotizing Pancreatitis: Advances in Management. Clin Surg. 2017; 2: 1437.