Evaluation of Coexistent Pathology in Patients with Breast Cancer Who Underwent Modified Radical Mastectomy (MRM) in Rasool-e- Akram Hospital between Years 2008-2014

Dina Rajabi far, Hamid reza Alizadeh otaghvar, Hamid reza Baradaran and Arefeh Zavari

Department of Breast Surgery, Iran University of Medical Science, Iran

^*Correspondance to: Arefeh Zavari 

 PDF  Full Text DOI: 10.25107/2474-1647.1343

Abstract

Introduction: Breast cancer is one of the most important and frequent cancer in women which increase in developing countries. It becomes major cause of death in women between ages 20-59 years. The most prevalent malignant tumor is Invasive Ductal Carcinoma (IDC). Pathology reports play an important role in diagnosis, prognosis and treatment of patients. So, we decided to evaluate the prevalence of coexistent pathology in patients with breast cancer who underwent MRM surgery.Methods and Materials: We study all patients who underwent MRM surgery between years 2008- 2014 in Rasool-e-Akram hospital. We evaluate electronic documents and pathology reports of patients and analyze all variants in spss v.18 software.
Results: We have 72 cases which 2 of them are men and the rest are women. The mean age is 50.56 year. (Min=27 yrs, max= 86 yrs). The main pathologies are IDC, DCIS, ILC, LCIS, Tubulolobular Carcinoma and the most prevalent one is IDC. In 61.1% of patients, coexistent pathology is reported and the most prevalent one is Fibrocystic changes (84.1%). The other coexistence pathologies are: Ductal Hypeplasia (31.8%), Adenosis (20.5%), Intraductal Papilloma (6.8%), Fibroadenomatoid changes (6.8%), Stromal Fibrosis (4.5%), Columar changes (2.3%), Apocrine Metaplasia (2.3%), Hypersecretory hyperplasia (2.3%), Lobular Hyperplasia (2.3%), Adenomyoepitheliomatosis (2.3%). There is no significant correlation between main pathology and presence of coexistent pathology. (Sig =0.47).Conclusion: Overlay, the most prevalent main pathology is IDC and Coexistent pathology is fibrocystic changes. There is no significant relation between main pathology and coexistent pathology.

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Cite the article

Dina Rajabi far, Hamid reza Alizadeh otaghvar, Hamid reza Baradaran, Arefeh Zavari. Evaluation of Coexistent Pathology in Patients with Breast Cancer Who Underwent Modified Radical Mastectomy (MRM) in Rasool-e- Akram Hospital between Years 2008-2014. Clin Surg. 2017; 2: 1343.