Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Neurological Surgery
  •  Otolaryngology - Head and Neck Surgery
  •  Vascular Surgery
  •  Endocrine Surgery
  •  Robotic Surgery
  •  Pediatric Surgery
  •  Minimally Invasive Surgery
  •  Oral and Maxillofacial Surgery


Citation: Clin Surg. 2019;4(1):2573.Research Article | Open Access

Study on Risk Factors and Prognosis of Lymph Node Metastasis of Siewert II/III Adenocarcinoma of Esophagogastric Junction

Tang Huazhen, Zhengzhi, Yinjie, Caijun, Zhang Jun and Zhang Zhongtao

Department of Surgery, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China

*Correspondance to: Zhang Jun 

 PDF  Full Text DOI: 10.25107/2474-1647.2573


Purpose: This study aimed to explore the risk factors and prognosis of lymph node metastasis in patients with Siewert II/III AEG. Methods and Materials: 65 Siewert II/III AEG patients undergoing surgical treatment (open or laparoscopic surgery) from July 2013 to May 2017, with complete clinical data from Beijing Friendship Hospital were included in the study. Patients were followed up until September 2017. Results: Multivariate analysis revealed that histological classification (OR=3.437, 95% CI: 1.046~11.294, P=0.042) and intravascular cancer embolus (OR=6.614, 95% CI: 1.942~22.524, P=0.003) were correlated with lymph node metastasis. Lymph nodes No. 1, 2, 3, 7, 11 and 110 groups showed a high lymph node metastatic rate. The 3-year overall survival analysis revealed that lymph node metastasis (P=0.167) and tumor staging (P=0.429) showed no significant differences. Conclusion: Histological type and vascular neoplasia are risk factors of lymph node metastasis. For Siewert II/III AEG patients, radical total gastrectomy combined with D2 lymphatic nodes dissection was suggested, No. 110 lymph nodes should be also dissected routinely. However, the long-term prognosis remains to be further studied.


Adenocarcinoma of esophagogastric junction; Siewert II/III; Logistic regression analysis; Lymphatic metastasis; Survival analysis

Cite the article

Huazhen T, Zhengzhi, Yinjie, Caijun, Jun Z, Zhongtao Z. Study on Risk Factors and Prognosis of Lymph Node Metastasis of Siewert II/III Adenocarcinoma of Esophagogastric Junction. Clin Surg. 2019; 4: 2573..

Search Our Journal

Journal Indexed In

Articles in PubMed

Antimicrobial Peptides: A Potential Therapeutic Option for Surgical Site Infections
 PubMed  PMC  PDF  Full Text
Mesh Sprayer Device with Liquefied Mesh Delivery System: Proposed Alternative for Currently Available Meshes in Hernia Repair and Supplement to Abdominal Closure
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Vertebral Endplate, Posterior Ligamentous Complex and Neural Dysfunction: Key Factors for Posterior Fusion Strategy in Thoracolumbar Fractures
 Abstract  PDF  Full Text
Correlation between Characteristics of Lymph Node Metastasis and Prognosis of N1-N2 Stage Non-small Cell Lung Cancer
 Abstract  PDF  Full Text
View More...