A Case of Takotsubo Cardiomyopathy Possibly Induced by Cilostazol Administration

Fukata M, Hatakeyama K, Yokoyama T, Nakamura H, Yasuda S, Muta T, Odashiro K, MaruyamaT and Akashi K

Department of Medicine and Biosystemic Science, Kyushu University Faculty of Medicine, Japan
Division for Student Counseling and Guidance, Faculty of Arts and Science, Japan

^*Correspondance to: Mitsuhiro Fukata 

 PDF  Full Text DOI: 10.25107/2474-1647.1010

Abstract

Takotsubo cardiomyopathy is a transient cardiac syndrome that involves left ventricular apical akinesis typically triggered by a significant emotional or physical stress. Here, we report a patient who presented with strong chest discomfort with left ventricular apical akinesis following cilostazol administration and was diagnosed with Takotsubo cardiomyopathy. Sudden onset of the disease immediately after cilostazol administration and no preceding emotional or physical stressors suggested that the pharmacological activity of cilostazol had triggered Takotsubo cardiomyopathy. Following the discontinuation of cilostazol and heart failure treatment, left ventricular dysfunction had fully recovered.

Keywords

Takotsubo cardiomyopathy; Cilostazol; Cyclic AMP; Left ventricular obstruction

Cite the article

Fukata M, Hatakeyama K, Yokoyama T, Nakamura H, Yasuda S, Muta T. A Case of Takotsubo Cardiomyopathy Possibly Induced by Cilostazol Administration. Clin Surg. 2016; 1: 1010.