Mini Review
What Surgeons Need to Know About Preoperative Cardiovascular Evaluation for Non-Cardiac Surgery
Basel Al Aloul*
Department of Interventional Cardiology, Leesburg Regional Medical Center, USA
*Corresponding author: Basel Al Aloul, Department of Interventional Cardiology, Leesburg Regional Medical Center, 1050 Old Camp Road, The Villages, Florida 32162, USA
Published: 29 Mar, 2017
Cite this article as: Al Aloul B. What Surgeons Need
to Know About Preoperative
Cardiovascular Evaluation for Non-
Cardiac Surgery. Clin Surg. 2017; 2:
1370.
Abstract
Perioperative major cardiovascular events can occur in patients undergoing non-cardiac surgery. Preoperative cardiovascular evaluation is performed in order to risk stratify these patients and help minimize potential non-surgical complications. The aim of this article is to summarize the American College of Cardiology and American heart association guidelines for preoperative cardiac evaluation of patients undergoing non-cardiac surgery in a simplified stepwise approach.
Introduction
Perioperative mortality and morbidity due to coronary artery disease (CAD) are known complications of non-cardiac surgery [1]. Therefore, cardiovascular evaluation is frequently performed and non-cardiac surgeons need to be part of this evaluation. Stratifying patients to low, intermediate and high risk profiles allow better planning and management of the proposed surgery and will help minimize unforeseen complications. When Cardiologists or internists get consulted to do a preoperative cardiovascular evaluation, the 5 following points are addressed.
Procedure Urgency
There are four procedure types according to urgency. An emergency procedure is one in which life or limb is threatened if not in the operating room, where there is time for no or very limited clinical evaluation, typically within <6 h. An urgent procedure is one in which there may be time for a limited clinical evaluation, usually when life or limb is threatened if not in the operating room, typically between 6 and 24 h. A time-sensitive procedure is one in which a delay of >1 to 6 weeks to allow for an evaluation and significant changes in management will negatively affect outcome. An elective procedure is one in which the procedure could be delayed for up to 1 year [1].
Procedure Risk
High risk procedure >5% risk and includes; emergent, aortic, peripheral vascular, anticipated prolonged surgical time associated with large fluid shifts. Intermediate risk 1-5% risk and includes carotid end arterectomy, head and neck surgery, intra peritoneal or intra thoracic, orthopedic, and prostate. Low risk <1% risk and includes; endoscopic, superficial, cataract, and breast surgery [1]. In is important to note that open abdominal aortic aneurysm surgery is high risk but, endovascular abdominal aortic aneurysm repair is not high risk.
Patient Risk
Patient risk factors include; CAD, heart failure, cardiomyopathy, valvular heart disease, arrhythmias, pulmonary vascular disease, and adult congenital heart disease. It is important to include clinical predictors of increased perioperative risk;
Major risk
Unstable angina or myocardial infarctions within past 30 days decompensate congestive heart
failure, significant arrhythmias, and severe valvular disease.
Intermediate risk
Mild angina (class I/II), prior myocardial infarction, compensated congestive heart failure,
diabetes and chronic kidney disease.
Minor risk
Age, abnormal ECG, rhythm other than sinus, decrease in functional status, history of
cerebrovascular accident and uncontrolled hypertension.
Calculation of Risk
There are 3 validated risk-prediction tools that can be useful in
predicting the risk of perioperative major cardiovascular events in
patients undergoing non-cardiac surgery. Many cardiologists prefer
Gupta perioperative risk calculator due to its simplicity [2].
• American College of Surgeons National Surgical Quality
Improvement Program Myocardial Infarction Cardiac Arrest
(NSQIP MICA). Known as Gupta Perioperative risk calculator [2].
• Revised Cardiac Risk Index (RCRI) [3].
• American College of Surgeons Surgical Risk Calculator
National Surgical Quality.
• Improvement Program (NSQIP) [4].
Preoperative Cardiac Testing
It is important to assess functional capacity either by questioning
the patient or by performing exercise stress testing.
Exercise and functional capacity
Functional status is a reliable predictor of perioperative and
long-term cardiac events. If a patient has not had a recent exercise
test before non-cardiac surgery, functional status can usually be
estimated from activities of daily living [5]. Functional capacity is
often expressed in terms of metabolic equivalents (METs), where 1
MET is the resting or basal oxygen consumption of a 40 year-old,
70-kg male. Functional capacity is classified as excellent (>10 METs),
good (7 METs to 10 METs), moderate (4 METs to 6 METs), poor
(<4 METs), or unknown. Patients unable to perform 4 METs of
work during daily activities are at a higher perioperative cardiac risk.
Examples of activities with <4 METs are golfing with a cart, slow
ballroom dancing, playing a musical instrument, and walking at
approximately 2 mph to 3 mph. Examples of activities with >4 METs
are climbing one flight of stairs or walking up a hill, walking on level
ground at 4 mph, and performing heavy work around the house.
The DASI (Duke Activity Status Index) is another method to assess
functional status [6].
Stepwise approach to perioperative cardiac assessment
The American College of Cardiology and American heart
association endorses the following treatment algorithm [1];
• Step 1: Patient scheduled for surgery with known risk
factors for CAD. Is the surgery Emergency? If yes then perform
clinical risk stratification and proceed with surgery without delay. If
no then proceed to step 2.
• Step 2: Does the patient have acute coronary syndrome
(ACS)? If yes then evaluate and treat according to guidelines directed
medical treatment and perform surgery when patient is stable from
an ACS point of view. If no then proceed to step 3.
• Step 3: Estimate perioperative risk of major cardiovascular
events based on combined clinical and surgical risk calculators
mentioned before then proceeds to step 4.
• Step 4: If low risk surgery <1% then no further cardiac
testing (class III to perform testing). Proceed with surgery.
• Step 5: If intermediate (1-5%) or high risk (>5%) surgery
then assesses functional capacity. If ≥4 METs then proceed with
surgery without further cardiac testing. If <4 METs or functional
capacity is unknown or cannot be determined proceed to step 6.
• Step 6: Will further testing impact decision making or
perioperative care? If yes then perform pharmacological stress testing
(class IIa). If the stress test is normal then proceed with surgery. If
abnormal then postpone the surgery and proceed with coronary
revascularization (class I). If further testing will not impact decision
making or perioperative care proceed to step 7.
• Step 7: Proceed with surgery according to guideline
directed medical treatment or consider alternative strategies such as
non-invasive treatment or palliation [1].
It is important to individualize patient evaluation. For example,
not every positive stress test needs further risk stratification with
coronary angiography. Stable asymptomatic patients with low and
intermediate risk positive stress testing, may proceed with their
planned surgery without further testing. This is due to the fact that
there is no evidence in such patients that coronary intervention
before non-cardiac surgery will improve their outcome and that
Antiplatelet interruption can lead to major cardiovascular events
in the perioperative period. Moreover, if the patient had coronary
revascularization in past 5 years and has no change in symptoms, the
patient can proceed to surgery without further testing. Also, if the
patient has history of CAD with a normal stress test in past 2 years
without new symptoms, the patient can proceed to surgery without
further testing.
Conclusion
Preoperative cardiovascular before non-cardiac surgery can be simple and clear if the above 7 step algorithm is followed. Preoperative evaluation should be individualized according to patient risk profile and should be a team approach that includes the patients’ cardiologist, internist, anesthetist and surgeon performing the noncardiac surgery. This team approach will minimize patient risk of complications.
References
- Fleisher LA, Fleischmann KE, Auerbach AD, Barnason SA, Beckman JA, Bozkurt B, et al. American College of Cardiology; American Heart Association. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. J Am Coll Cardiol. 2014;64:e77-137.
- Gupta PK, Gupta H, Sundaram A, Kaushik M, Fang X, Miller WJ, et al. Development and validation of a risk calculator for prediction of cardiac risk after surgery. Circulation. 2011;124:381-7.
- Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100:1043-9.
- Cohen ME, Ko CY, Bilimoria KY, Zhou L, Huffman K, Wang X, et al. Optimizing ACS NSQIP modeling for evaluation of surgical quality and risk: patient risk adjustment, procedure mix adjustment, shrinkage adjustment, and surgical focus. J Am Coll Surg. 2013;217:336-46.
- Reilly DF, McNeely MJ, Doerner D, Greenberg DL, Staiger TO, Geist MJ, et al. Self-reported exercise tolerance and the risk of serious perioperative complications. Arch Intern Med. 1999;159:2185-92.
- Hlatky MA, Boineau RE, Higginbotham MB, Lee KL, Mark DB, Califf RM, et al. A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index). Am J Cardiol. 1989;64:651-4.