Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Robotic Surgery
- Endocrine Surgery
- Thoracic Surgery
- Pediatric Surgery
- Obstetrics Surgery
- Minimally Invasive Surgery
- Otolaryngology - Head and Neck Surgery
- Ophthalmic Surgery
Abstract
Citation: Clin Surg. 2023;8(1):3660.Clinical Image | Open Access
Corneal Neurotization in the Setting of Previous Orbital Radiation Therapy
Fan J, Goldberg H, Anthony C and Esmaeli B
Department of Plastic Surgery, Orbital Oncology & Ophthalmic Plastic Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
*Correspondance to: Bita Esmaeli
PDF Full Text DOI: 10.25107/2474-1647.3660
Abstract
A 55-year-old man, a renal transplant patient with immunosuppression, presented with left midface squamous cell carcinoma with perineural spread to the skull base, leading to left corneal anesthesia and facial paralysis. His tumor was deemed surgically unresectable. He was treated with chemotherapy and high dose orbital and skull base radiation (total dose of 68 Gy). He had progressive corneal scarring and opacification despite upper eyelid weight placement, ectropion repair, and tarsorrhaphy (Figure 1A). He underwent Corneal Neurotization (CN) with sural nerve autograft coapted to the contralateral supraorbital trunk (Figure 1B), leading to marked improvement in corneal health and visual function (Figure 1C). CN is a relatively new surgical procedure for treatment of neurotrophic keratopathy [1,2]. Patients with multiple cranial neuropathies secondary to skull base tumors are at risk for severe corneal complications due to coincidence of facial paralysis and corneal anesthesia [3,4]. To our knowledge, this is the first case documenting CN in a patient who has had high dose orbital radiation therapy. CN has been thus far viewed as contraindicated after high dose orbital radiation. Coaptation of the sural nerve to the non-radiated contralateral supraorbital nerve was done as the ipsilateral supraorbital nerve was damaged from previous exposure to high dose radiation. Our patient experienced marked improvement in corneal health after CN.
Keywords
Cite the article
Fan J, Goldberg H, Anthony C, Esmaeli B. Corneal Neurotization in the Setting of Previous Orbital Radiation Therapy. Clin Surg. 2023; 8:3660.