Necrotizing Fasciitis with Thrombus due to Multidrug Resistant Acinetobacter baumanii Infection

Li De Lun1 and Dong Ming Li2*

1Department of Nephrology and Rheumatology, Air Force General Hospital, China
2Department of Dermatology and Laboratory of Mycology, Peking University Third Hospital, China

^*Correspondance to: Dong Ming Li 

 PDF  Full Text DOI: 10.25107/2474-1647.3456

Abstract

This report describes a 53 year old man who died of necrotizing fasciitis caused by multidrugresistant Acinetobacter baumannii infection, characterized by fever, leg pain and swelling. He was treated with cefotaxine, vancomycin and levofloxacin in a local hospital, but did not respond. Physical examination showed high fever and flaring red indurate swelling with severe tenderness along his right leg. Five sets of fascia yielded multidrug-resistant A. baumannii. Pathology showed extensive necrosis with thrombi and inflammatory cell infiltration, in which rod-shaped bacteria were seen in macrophages. Immunohistochemical analysis confirmed that most macrophages had NK/T cell markers. The patient developed toxic shock due to multiple organ failure and died before receiving potent antibiotic treatment. Necrotizing fasciitis requires urgent treatment of infection related thrombosis while multidrug resistance and NK/T cells may obscure the nature of infection.

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Cite the article

De Lun L, Ming Li D. Necrotizing Fasciitis with Thrombus due to Multidrug Resistant Acinetobacter baumanii Infection. Clin Surg. 2022; 7: 3456..