Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Obstetrics Surgery
  •  Bariatric Surgery
  •  Colon and Rectal Surgery
  •  Robotic Surgery
  •  General Surgery
  •  Plastic Surgery
  •  Orthopaedic Surgery
  •  Pediatric Surgery


Citation: Clin Surg. 2020;5(1):2782.Case Report | Open Access

Rare Evolutionary Models in Child Neurofibromatosis - Case Report and Literature Review

Alina Mariela Murgu1,2,3, Geanina Irina Crişcov1,2,3*, Bogdan Savu1,2,4, Ginel Baciu5,6, Silvia Fotea5,6, Anca Chiriac7,8,9 and Elena Tarca1,2,4

1University of Medicine and Pharmacy “Gr. T. Popa”, Romania
2”St. Mary” Clinical Emergency Children Hospital, Romania
3Department of Pediatric, University of Medicine and Pharmacy “Gr. T. Popa”, Romania
4Department of Pediatric Surgery, University of Medicine and Pharmacy, “Grigore T. Popa”, Romania
5Department of Neonatology, Children Hospital –ICU, Galati, Romania
6Department of Neonatology, University of Medicine Galati, Romania
7Department of Dermatology, Apollonia University, Romania
8Nicolina Medical Center, Romania
9Petru Poni Institute of Macromolecular Center Chemistry, Iasi, Romania

*Correspondance to: Geanina Irina Crişcov 

 PDF  Full Text DOI: 10.25107/2474-1647.2782


Rationale: Neurofibromatosis is a multisystem genetic disorder that is characterized by cutaneous findings, multi-systemic impairment and neurofibromas occurring in the nervous system. Patient Concerns: We present two cases of Neurofibromatosis type1, which developed a rare progressive polypoid injury-like complication in the gallbladder and duodenum, possibly neurofibromas. Diagnosis: Both cases required detailed clinical examination, biological investigations, abdominal ultrasound, MRI, digestive endoscopy and histo-pathological diagnosis. Interventions: The treatment required multidisciplinary involvement: Pediatrician, geneticist, dermatologist, pediatric surgeon, anatomy pathologist. Outcomes Lessons: With proper and prompt treatment, the evolution was good. Although rare, gastrointestinal damage should be considered in a patient with NF who has recurrent abdominal pain. Digestive neurofibromas may have different locations and the possible complications depending on their location.


Neurofibromatosis; Cafe-au-lait spots; Neurofibromas; Gastrointestinal stromal tumor; Gastrointestinal polyposis

Cite the article

Murgu AM, Crişcov GI, Savu B, Baciu G, Fotea S, Chiriac A, et al. Rare Evolutionary Models in Child Neurofibromatosis - Case Report and Literature Review. Clin Surg. 2020; 5: 2782..

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