Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Vascular Surgery
  •  Gynecological Surgery
  •  Obstetrics Surgery
  •  Neurological Surgery
  •  Gastroenterological Surgery
  •  Emergency Surgery
  •  Ophthalmic Surgery
  •  Cardiovascular Surgery


Citation: Clin Surg. 2020;5(1):2730.Case Report | Open Access

Oral and Maxillofacial Langerhans Cell Histiocytosis: A Rare Case Report and Literature Review

Zhihui Tian*

Department of Oral and Maxillofacial Surgery, Southern Medical University, China

*Correspondance to: Zhihui Tian 

 PDF  Full Text DOI: 10.25107/2474-1647.2730


Langerhans Cell Histiocytosis (LCH) is a rather rare tumor derived from myeloid dendritic cells and featured by the ontogenesis and dissemination of CD1a+/CD207+ LCH cells affecting oral and maxillofacial region in most cases. We reported a case of rapid progressive LCH involving bilateral mandible, including one relapse in situ in a male adult patient with a history of repetitive dental interventions. No cases have previously been reported in literature associating external trauma history with the acceleration of the disease course. Diagnostic criteria for differentiation between maxillofacial LCH and periodontitis are also presented based on clinical observation and literature review.


Langerhans Cell Histiocytosis (LCH); Trauma; Oral cancer

Cite the article

Tian Z. Oral and Maxillofacial Langerhans Cell Histiocytosis: A Rare Case Report and Literature Review. Clin Surg. 2020; 5: 2730..

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