Early Results of Negative Pressure Wound Therapy in Treatment of Chronic Wounds

Abd Elrahman*

Department of General Surgery, El Sahel Teaching Hospital, Egypt

^*Correspondance to: Abd Elrahman 

 PDF  Full Text DOI: 10.25107/2474-1647.2711

Abstract

Background: Chronic wounds may affect only the epidermis and dermis, or they may affect tissues all the way to the fascia. Chronic wounds seem to be detained in one or more of the phases of wound healing. For example, chronic wounds often remain in the inflammatory stage for too long. Negative-Pressure Wound Therapy (NPWT) devices are designed to apply controlled suction to a wound bed at continuous or intermittent pressure settings to stimulate wound closure. Aim: Assess the effect of negative pressure wound therapy in management of chronic wound. Methods: This is prospective study was conducted on 60 Egyptian volunteers participated; they were 40 males and 20 females, between the age of 20 and 60 years. This study was conducted from May 2017 to May 2018 El Sahel Teaching Hospital. Results: VAC therapy, together with periodical surgical wound debridement and specific antibiotic therapy could be helpful to promote and accelerate wound healing of foot lesions after restoration of an adequate distal blood flow through surgical revascularization or angioplasty. Conclusion: Negative-Pressure Wound Therapy (NPWT) devices are designed to apply controlled suction to a wound bed at continuous or intermittent pressure settings to stimulate wound closure. Negative pressure can result in numerous alterations in the wound environment, including removal of excess exudate containing high concentrations of proteases and inflammatory cytokines, stimulation of senescent cells, mobilization of macrophages, and stimulation of angiogenesis.

Keywords

Negative pressure wound therapy; Chronic wounds; Treatment; ROS

Cite the article

Elrahman A. Early Results of Negative Pressure Wound Therapy in Treatment of Chronic Wounds. Clin Surg. 2020; 5: 2711..