Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Obstetrics Surgery
  •  Robotic Surgery
  •  Orthopaedic Surgery
  •  Surgical Oncology
  •  General Surgery
  •  Colon and Rectal Surgery
  •  Breast Surgery
  •  Urology


Citation: Clin Surg. 2021;6(1):3130.Review Article | Open Access

The Role of Negative Pressure Wound Therapy in Severe Acute Pancreatitis

Sass Tamás*, Tóth Fruzsina, Susán Zsolt, Sápy Péter and Szentkereszty Zsolt

Institute of Surgery, University of Debrecen, Debrecen, Hungary

*Correspondance to: Tamas S 

 PDF  Full Text DOI: 10.25107/2474-1647.3130


The use of negative pressure wound therapy is a well accepted method of choice in the treatment of complicated septic wounds. Beside its excellent effects on wound healing it is more often used in the abdominal-general surgical practice, as well as in acute pancreatitis. The aim of this review is to find evidences and to determine the role of negative pressure wound therapy in the treatment of severe acute pancreatitis based on the PubMed database. Open abdomen therapy with NPWT is the first of choice, when acute pancreatitis related abdominal compartment syndrome develops. In open abdomen -and open bursa- therapy for septic necrosis and intracutaneous fistulas the device can be used as an additional approach. In case of impossible abdominal wall closure, the vacuum therapy also has a beneficial effect. Vacuum therapy in combination with endoscopic transgastric drainage (Endo-VAC therapy) can be helpful in cases of walled-off pancreatic necrosis as a minimally invasive method. Beside the direct effects on wound healing NPWT significantly reduces morbidity and mortality in severe pancreatic necrosis; furthermore it simplifies nursing of patients, in this way reducing ICU and hospital stay. In conclusion, as an additional therapy NPWT is advised in severe acute pancreatitis, complicated with septic necrosis and/or ACS, or entero-atmospheric fistulas in critically ill patients.


Acute pancreatitis; Negative pressure wound therapy; Abdominal compartment syndrome

Cite the article

Tamás S, Fruzsina T, Zsolt S, Péter S, Zsolt S. The Role of Negative Pressure Wound Therapy in Severe Acute Pancreatitis. Clin Surg. 2021; 6: 3130..

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