Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Surgical Oncology
  •  Breast Surgery
  •  Pediatric Surgery
  •  Plastic Surgery
  •  Orthopaedic Surgery
  •  Otolaryngology - Head and Neck Surgery
  •  Transplant Surgery
  •  Obstetrics Surgery


Citation: Clin Surg. 2021;6(1):3114.Case Report | Open Access

Sudden Blood-Filled Bulla in Oral Cavity: Case Report

Hui-Wen Yang1,2 and Yu-Feng Huang1,2*

1 Department of Stomatology, Chung Shan Medical University Hospital, Taiwan 2 Department of Dentistry, Chung Shan Medical University, Taiwan

*Correspondance to: Yu-Feng Huang 

 PDF  Full Text DOI: 10.25107/2474-1647.3114


Purpura is a common and non-specific clinical term, which may involve different underlying disorders. Among all, immune thrombocytopenic purpura, also called Idiopathic Thrombocytopenic Purpura (ITP), is defined as isolated low platelet count without any other underlying causes of thrombocytopenia. ITP is an autoimmune disease with antibodies detectable against platelet surface antigens. The diagnosis of ITP needs to exclude blood abnormalities other than a low platelet count, and no physical signs other than bleeding. Co-existing causes including leukemia, medications (e.g., quinine, heparin), cirrhosis, HIV, hepatitis C also needed to be ruled out. The severity of ITP can be lethal and therefore it is worthwhile for all dentists to understand such diagnosis. Here we reported a case of ITP to demonstrate the urgency of the case. A 43 y/o female that came in to our oral pathology & diagnosis clinic on June 2016 showing blood-filled bulla in the mouth that developed overnight. At examination, blood-filled bullae noted on the tongue, buccal mucosa and lips. Petechia also noted on the skin. Complete blood count showed extremely lower platelet count (1000/ul). ITP was strongly suspected. Patient was immediately referred to emergency department for treatment. After 5 months of treatments including platelet transfusion, prednisolone, revolade, dapsone, platelet count returned to normal level.


Idiopathic thrombocytopenic purpura; Bulla; Petechia

Cite the article

Yang H-W, Huang Y-F. Sudden BloodFilled Bulla in Oral Cavity: Case Report. Clin Surg. 2021; 6: 3114.

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