Ulcerated Pseudoangiomatous Stromal Hyperplasia (PASH) of the Breast- A Rare Form of Presentation in a 13-Year-Old Girl

Vanessa Rebelo dos Santos*, Carlota Ramos, Joana Nolasco Vaz, Cátia Felício, Rogélio Andrés-Luna, Natália Alves and João Coutinho

Department of Surgery, Northern Lisbon University Hospital Centre, Portugal

^*Correspondance to: Vanessa Rebelo dos Santos 

 PDF  Full Text DOI: 10.25107/2474-1647.3098

Abstract

Pseudoangiomatous Stromal Hyperplasia (PASH) is a benign lesion of the breast characterized by proliferation of stromal mesenchymal cells of myofibroblastic origin and is thought to be hormonally driven. It is mainly found incidentally, but it may manifest as a large solid mass of the breast. Imaging findings of PASH are often nonspecific and it can be misdiagnosed with other benign and malignant lesions of the breast. Definitive diagnosis is mostly given by histologic examination with core-needle biopsy or surgical specimen sample. Surgical excision of the lesion with adequate margins of resection is the usual therapeutic approach, and with so, recurrence is low. We present a clinical case of a 13-year-old girl presenting with what we believe is the first reported case of PASH manifesting as an ulcerated tumor.

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Cite the article

Santos VRD, Ramos C, Vaz JN, Felício C, Andrés-Luna R, Alves N, et al. Ulcerated Pseudoangiomatous Stromal Hyperplasia (PASH) of the Breast- A Rare Form of Presentation in a 13-Year-Old Girl. Clin Surg. 2021; 6: 3098.