A Rare Manifestation of Primary Bony Non-Hodgkin’s Lymphoma of the Hand: A Case Report and Literature Review

Yueh-Ching Chang, Kuang-Ting Liu, Yu-Chieh Lin, Jui-Tien Shih and Junn-Liang Chang

Department of Pathology and Laboratory Medicine, Taoyuan Armed Forces General Hospital, Taiwan
Hsin Sheng Junior College of Medical Care and Management, Taiwan
Department of Orthopedic Surgery, Taoyuan Armed Forces General Hospital, Taiwan
Department of Biomedical Engineering, Ming Chuan University, Taiwan

^*Correspondance to: Junn-Liang Chang 

 PDF  Full Text DOI: 10.25107/2474-1647.2582

Abstract

Background: Primary bone non-Hodgkin's B-cell lymphoma is an extremely rare especially in the hand and only four cases with Diffuse Large B-Cell Lymphoma (DLBCL) of the hand have been reported in the worldwide. Case Report: We describe an additional case of 89-year old man with primary DLBCL of the hand with characteristic pathological fracture of the metacarpal bone of the thumb without Rheumatoid Arthritis (RA), autoimmune disease or Methotrexate (MTX) treatment and underwent the ORIF with K-wires implants with chemotherapy. Conclusion: The preoperative diagnosis for DLBCL is very difficult. Orthopedic surgeons should be acquainted with the differential diagnosis of primary bony lymphoma. The definite diagnosis is based on histopathological with Immunohistochemical (IHC) study and imaging examination, in which other disease lesions should be excluded.

Keywords

Non-Hodgkin’s lymphoma (NHL); Rheumatoid arthritis (RA); Diffuse large-Bcell lymphoma (DLBCL); Metacarpal; Immunohistochemical (IHC)

Cite the article

Chang Y-C, Liu K-T, Lin Y-C, Shih J-T, Chang J-L. A Rare Manifestation of Primary Bony Non-Hodgkin’s Lymphoma of the Hand: A Case Report and Literature Review. Clin Surg. 2019; 4: 2582..