Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
- Obstetrics Surgery
- Emergency Surgery
- Cardiovascular Surgery
- Transplant Surgery
- Gynecological Surgery
- Endocrine Surgery
- Gastroenterological Surgery
- Surgical Oncology
Citation: Clin Surg. 2019;4(1):2368.Research Article | Open Access
Department of General Surgery, GMC Srinagar, J&K, India
Department of Colorectal Surgery, SKIMS, India
Background: Colorectal Cancer (CRC) is a disease with a major worldwide burden in terms of patient sufferings and cost of treatment. The age-standardized rates of CRC in India are 4.2 and 3.2/ lac for males and females respectively.
Objective: To study the Clinico-pathological profile of colorectal cancer patients in Kashmir.
Methods: This 5 year study, conducted in Colorectal Division of Department of General and Minimal Access Surgery, Sher-i-Kashmir Institute of Medical Sciences (SKIMS) in Kashmir, included prospectively all the patients who presented with CRC from August 2014 to June 2016 and retrospectively the data of 3 years of all the patients with CRC was studied. Parameters studied were age, sex, site of lesion, clinical presentations and histology of the lesion.
Results: Among 930 patients included in this study, CRC was most common (24.2%) in the age group of 56 to 65 years. About 19.25% of patients were below the age of 35 years. Male to female ratio was 3:2 (p-value 0.011) and rural to urban ratio was 1.7:1 (p value 0.013). About 96% patients were non-vegetarian. About 50% of the patients had stage III disease at presentation and most patients (75%) presented with change in bowel habits. Recto-sigmoid involvement comprised about 54%. Preoperative CEA levels were elevated (≥ 5.1 ng/ml) in 50% patients. Proliferative type was the most common (n=386; 41.5%) morphology of tumor (p-value <0.0001). Most common morphological type of tumor in youngest age group (15 to 25 years) was infiltrative. Histologically 99% patients had adenocarcinoma and 50% of them were well differentiated.
Conclusion: Colorectal cancer is quite common in Kashmir Valley, involving mostly recto-sigmoid region and majority of our patients present in a locally advanced stage especially in younger agegroups.
Cancer; Colorectal; Colon; Rectum
Cite the article
Bhat SA, Chowdri NA, Khan MA, Parray FQ, Wani RA, Mehraj A, et al. Clinicopathological Profile of Colorectal Cancer in Kashmir. Clin Surg. 2019; 4: 2368.