Infiltration of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in the Prostatectomy Material in Patient with Symptoms of Prostatism and Multiple Bladder Stones

Funda Bozkurt, Yasemin Yuyucu Karabulut, Mesut Tek and Anıl Tombak

Department of Pathology, Mersin University School of Medicine, Turkey
Department of Urology, Mersin University School of Medicine, Turkey
Department of Hematology, Mersin University School of Medicine, Turkey

^*Correspondance to: Funda Bozkurt 

 PDF  Full Text DOI: 10.25107/2474-1647.2224

Abstract

Chronic lymphocytic leukemia/small lymphocytic lymphoma is a lymphoproliferative disease with bone marrow, peripheral blood, lymph node or various solid organ involvements. It may occur as a monotonous small lymphoid cell infiltration in the solid organs, rarely. This case is presented because of having chronic lymphocytic leukemia/small lymphocytic lymphoma infiltration in a prostatectomy material. A 77 year old male patient referred to urology clinic due to symptoms of prostatism. The patient was diagnosed with benign prostatic hyperplasia and underwent open prostatectomy. Histopathological examination revealed monotone, small lymphoid cell infiltration with an infiltrative distribution in the prostate stroma. In the immunohistochemical study, common strong cytoplasmic staining was detected in monotone lymphoid cells with CD20, CD5 and CD23. With these findings, the patient was diagnosed with chronic lymphocytic leukemia/ small lymphocytic lymphoma infiltration in the prostate. Chronic lymphocytic leukemia/small lymphocytic lymphoma cases presenting with lymphocytic infiltration of the prostate are quite rare. As noted in the literature on a small number of cases, most of the cases are detected during the investigation of obstructive symptoms. Leukemic infiltration should also be kept in mind when monotone lymphoid cells are present in the prostatectomy material.

Keywords

Prostate; Prostatectomy; Chronic lymphocytic leukemia/small lymphocytic lymphoma

Cite the article

Bozkurt F, Karabulut YY, Tek M, Tombak A. Infiltration of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in the Prostatectomy Material in Patient with Symptoms of Prostatism and Multiple Bladder Stones. Clin Surg. 2018; 3: 2224.