Pancreaticoduodenectomy Following Chemotherapy for Locally Advanced Adenocarcinoma of the Pancreatic Head: Case Report

Amine Chhaidar and Ali Ben Ali

Department of General Surgery, Sahloul University Hospital, Tunisia

^*Correspondance to: Amine Chhaidar 

 PDF  Full Text DOI: 10.25107/2474-1647.2186

Abstract

Context: Pancreatic ductal adenocarcinoma is the fourth leading cause of cancer-related mortality. It has an extremely poor prognosis and prolonged survival is achieved only by resection with macroscopic tumor clearance. Locally advanced pancreatic adenocarcinoma is characterized by the abutment or invasion of major vascular structures preventing surgeons from achieving optimal R0 resection.Aims: We report a case of 52 years old patient with locally advanced, unresectable pancreatic ductal adenocarcinoma. The patient was treated initially with neoadjuvant chemotherapy and subsequent radical surgery. An objective response was obtained and the patient’s health improved.Conclusion: Patients with locally advanced/unresectable tumors should be included in neoadjuvant protocols and subsequently be reevaluated for resection, which is possible in a relevant number of patients.

Keywords

Pancreatic adenocarcinoma; Neoadjuvant chemotherapy; SMV

Cite the article

Chhaidar A, Ben Ali A. Pancreaticoduodenectomy Following Chemotherapy for Locally Advanced Adenocarcinoma of the Pancreatic Head: Case Report. Clin Surg. 2018; 3: 2186.