Intra-Arterial Hepatic Perfusion for Metastatic Melanoma of Cutaneous Origin

Sean J.Judge, Amanda R.Kirane and Sepideh Gholami

Department of Surgery, University of California, USA

^*Correspondance to: Sepideh Gholami 

 PDF  Full Text DOI: 10.25107/2474-1647.2165

Abstract

Intra-arterial Hepatic Perfusion (IHP) is a chemotherapeutic strategy that has been in use for several years. Its application in non-resectable liver metastases has gained increased acceptance following favorable results from recent clinical studies. Most of these published studies focus on outcomes of metastatic colorectal and ocular melanoma due to the high frequency of isolated liver metastases. To better understand the role of IHP in metastatic melanoma, we reviewed the pertinent literature with a focus on cutaneous melanoma. Here we present a brief report of IHP for metastatic melanoma of cutaneous origin. We have highlighted the available data on patient outcomes with attention to the unique morbidity and mortality, and future directions of IHP therapy.

Keywords

Intra-arterial hepatic perfusion; Regional therapies; Metastatic melanoma; Cutaneous melanoma

Cite the article

Judge SJ, Kirane AR, Gholami S. Intra-Arterial Hepatic Perfusion for Metastatic Melanoma of Cutaneous Origin. Clin Surg. 2018; 3: 2165.