Use of Polyethylene Glycol in Whole Bowel Irrigation and Comparing of Systemic Effects with Lactated Ringer’s Solution

Emine Ince and Mehmet Emine Senocak

Departments of Pediatric Surgery, Başkent University, Turkey
Departments of Pediatric Surgery, Hacettepe University, Turkey

^*Correspondance to: Emine Ince 

 PDF  Full Text DOI: 10.25107/2474-1647.2100

Abstract

Aim: Whole Bowel Irrigation (WBI) has been used for many different purposes, especially in before large bowel surgery and colonoscopy. Some studies have reported that the lactated Ringer’s (RL) solution has choleretic effect and the Polyethylene Glycol (PEG) solution may produce liver necrosis. The aim of this study is to show the systemic effects of PEG in WBI and comparing with RL solution to determine the most reliable one.Methods: Forty patients who underwent WBI with PEG and RL were studied. Vital signs, electrolyte levels, liver function, hemorrhage parameters and blood table were checked before and after the procedure. Vomiting and unrest complaints were noted to tolerance reagent. The amount of solution, the duration and the efficacy of the procedure were identified.Results: WBI completed at the same time in PEG and RL group under-7 years old children. Patients used PEG were found to be better for patient compliance in 7 years old and over group, and time was decreased to 4 hours. The amount of solution was 3.2 ± 0.11 / L in PEG and 8.4 ± 0.02 / L in RL, significant difference (p<0.05). RL solution caused to be increased Na and Cl blood level (p<0.05) and PEG solution caused to be decreased K blood level (p<0.05). For liver functional test there were no significantly differences between PEG and RL solutions.Conclusion: Evaluating for tolerance, used amount and liver influence, PEG is more preferable solution compared with RL especially for 7 years old and over children.

Keywords

Whole bowel irrigation; Polyethylene glycol; Ringer lactate

Cite the article

Ince E, Senocak ME. Use of Polyethylene Glycol in Whole Bowel Irrigation and Comparing of Systemic Effects with Lactated Ringer’s Solution. Clin Surg. 2018; 3: 2100.