Sinus of Valsalva Aneurysm – A Possible Association with Infection of Lymphatic Mode of Spread: Report of 15 Cases

Lupinski Ryszard

Department of Cardiothoracic Surgery, National Heart Department of Centre, Singapore
Department of Cardiothoracic Surgery, University of Cape Town, South Africa

^*Correspondance to: Lupinski Ryszard 

 PDF  Full Text DOI: 10.25107/2474-1647.2013

Abstract

Objective: Sinus of Valsalva Aneurysm (SoVA) is a rare cardiac defect. Both congenital and acquired aetiology of SoVA have been proposed. It was the aim of this study to describe the clinical presentation of SoVA and to investigate the possible association with infectious disease in these patients.Methods: Fifteen patients with SoVA were identified. Patient case notes were retrieved and reviewed. Patients were 7 females and 8 males with a mean age of 31 years (range 10-56). Seven patients were South African Bantu, six were Chinese and two were Caucasians.Results: Chronic chest infections not responding to routine antibiotics treatment were diagnosed in seven patients, tuberculosis and syphilis were each diagnosed in two patients and one patient had pharymgitis. Three patients had no significant medical history of infection. Intrathoracic lymphadenopathy was observed in 10 of 13 patients with recorded findings.Conclusion: Sinus of Valsalva Aneurysm seems to have strong association with infections of lymphatic mode of spread. These infections have developed prior diagnosis of SoVA was made in majority of patients.

Keywords

Cite the article

Ryszard L. Sinus of Valsalva Aneurysm – A Possible Association with Infection of Lymphatic Mode of Spread: Report of 15 Cases. Clin Surg. 2018; 3: 2013.