Laparoscopic Surgery Effects Thyroid Functions

Ali Uzunkoy

Department of General Surgery, Harran University School of Medicine, Turkey

^*Correspondance to: Ali Uzunkoy 

 PDF  Full Text DOI: 10.25107/2474-1647.1980

Abstract

Introduction: Serum concentrations of thyroid hormones may be affected during course of nonthyroidal illnesses such as sepsis, surgery, myocardial infarction, bypass surgery, starvation, bone marrow transplantation. This condition is defined as "sick euthyroid syndrome”. Surgical trauma is one of the factors, in which the serum thyroid hormone levels were affected in the absence of abnormalities in thyroid gland functions. The influences of surgical trauma on serum level of thyroid hormones have been investigated in several studies. However, there are controversial findings exists about the changes of the serum levels. Surgical trauma causes endocrine and immune responses related with the degree of trauma. It is well known that laparoscopic operations cause less tissue injury and systemic stress responses than open surgery. There are a few available reports about the effect of laparoscopic surgery on serum thyroid hormone levels. The aim of this study was to evaluate the effects of surgery trauma on thyroid functions in subjects underwent laparoscopic cholecystectomy.Patients and
Methods: Forty subjects who undergoing elective laparoscopic cholecystectomy for gallstone disease were included in this study. The patients who have thyroidal and endocrinological disorders were excluded from this study. Preoperative values of thyroid function tests evaluated. The euthyroid patients were included in this study. The cases were operated on same anaesthetic protocol with general anaesthesia and standard laparoscopic technique using 4 trocars. The patients who converted to open procedure were excluded from this study. Venous blood samples were taken before operation 30th min and 2nd and 24th hr afterwards for measurement of the levels of TSH, free triiodothyronine (T3), total T3, free thyroxin (T4), total T4, cortisole and albumin.

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Cite the article

Uzunkoy A. Laparoscopic Surgery Effects Thyroid Functions. Clin Surg. 2018; 3: 1980.