Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Ophthalmic Surgery
- Gastroenterological Surgery
- Gynecological Surgery
- Emergency Surgery
- Otolaryngology - Head and Neck Surgery
- Orthopaedic Surgery
- General Surgery
- Bariatric Surgery
Abstract
Citation: Clin Surg. 2018;3(1):1861.Research Article | Open Access
Clinical Significance of Lipid Metabolism in Evaluating the Prognosis of Hyperlipidemic Acute Pancreatitis
Gai Ji-qin, Ni Lei, Qin Jian-min
Department of General Surgery, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China Department of General Surgery, Affiliated Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 201805, China
*Correspondance to: Qin Jian-min
PDF Full Text DOI: 10.25107/2474-1647.1861
Abstract
Objective: To investigate the correlation between serum lipid metabolic indicators and MCTSI score in hyperlipidemic acute pancreatitis.Methods: The serum lipid metabolic indicators and MCTSI scores of 97 cases of hyperlipidemic acute pancreatitis were retrospectively analyzed from Jul. 2012 to Jul. 2016. The correlation of serum lipid metabolic indicators and MCTSI score were analyzed.Results: There existed statistically significant difference of the apoA1 levels of patients among MCTSI score =2, =4, and ≥6 group, and the higher the MCTSI score was, the lower the apoA1 level was (F=10.004, P<0.01). The serum apoA1 level of hyperlipidemic acute pancreatitis patient was negatively correlated with MCTSI score(rs = -0.420, P<0.01). In the patients with lower serum apoA1 values, the number of patients whose MCTSI scores were ≥4 was significantly more than that of those whose MCTSI scores were 2(χ2 =9.343, P<0.01). But there existed no statistically significant difference of serum TG, TC, HDL-C, LDH-C, apoB and LP(A) levels among patients with MCTSI score =2, =4, and ≥6 group (F=1.358, 0.585, 0.049, 0.439, 0.228, 0.168, P>0.05). There was no correlation between the levels of serum TG, TC, HDL-C, LDL-C, apoB, and Lp(A) and MCTSI score(rs=0.014, 0.036, -0.061, -0.050, -0.008, -0.004, P>0.05).Conclusion: Serum apoA1 level is a better indicator to evaluate the severity of hyperlipidemic acute pancreatitis. There is negative correlation between severity of hyperlipidemic acute pancreatitis and serum apoA1 level.
Keywords
Hyperlipidemic acute pancreatitis; Lipid; Apolipoprotein; MCTSI
Cite the article
Ji-qin G, Lei N, Jian-min Q. Clinical Significance of Lipid Metabolism in Evaluating the Prognosis of Hyperlipidemic Acute Pancreatitis. Clin Surg. 2018; 3: 1861.