Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Minimally Invasive Surgery
  •  Colon and Rectal Surgery
  •  Orthopaedic Surgery
  •  Breast Surgery
  •  Cardiovascular Surgery
  •  Vascular Surgery
  •  Urology
  •  Plastic Surgery

Abstract

Citation: Clin Surg. 2017;2(1):1666.Research Article | Open Access

Primary Lung Tumors in Children and Adolescents: 29 Years of Experience at a Single Institution

Fazal N Wahid, Alpin D Malkan, Armita Bahrami, Alberto S Pappo, John A Sandoval, Israel Fernandez-Pineda and Bhaskar N Rao

Department of Pediatric Surgery, King Saud Medical City, Riyadh Saudi Arabia
Department of Pathology, St Jude Children's Research Hospital, Memphis, TN, USA
Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN, USA

*Correspondance to: Bhaskar N Rao 

 PDF  Full Text DOI: 10.25107/2474-1647.1666

Abstract

Purpose: Primary lung tumors in children are rare and comprise a broad range of histopathologic types. The incidence and outcome of these lesions are still largely unknown. We investigated the relative incidence of different primary lung tumors and their outcomes in children and adolescents at a single pediatric institution.Methods: All patients diagnosed with primary lung tumors from 1984 through 2013 were retrospectively reviewed. Data were collected from medical records after approval was obtained from our Institutional Review Board.Results: Seventeen-patients (8 boys, 9 girls) were identified with a mean age of 9.3 years (range: newborn to 18 years). Seven distinct histopathologic tumor types were identified: inflammatory myofibroblastic tumor (4), pleuropulmonary blastoma (4), carcinoid (n=3), mucoepidermoid carcinoma (2), synovial sarcoma (1), pulmonary hamartoma (2), and infantile fibrosarcoma (1). Chemotherapy was used in 37.5% (n=6) and radiation in 25% (4) of patients. The mortality rate was 25% (n=4), but only two deaths (12.5%) were directly related to the lung tumors. Of the 12 survivors, median duration of follow-up was 8.75 years (range, 0.5-20.4 years). One patient was lost to follow-up.Conclusions: Our experience substantiates the rarity and histopathological diversity of primary lung tumors in pediatric patients. Although complete resection remains the standard of care for most lung tumors, the role of adjuvant therapy is dependent on the histopathologic tumor type.

Keywords

Cite the article

Wahid FN, Malkan AD, Bahrami A, Pappo AS, Sandoval JA, Fernandez-Pineda I. Primary Lung Tumors in Children and Adolescents: 29 Years of Experience at a Single Institution. Clin Surg. 2017; 2: 1666.

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