
Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Colon and Rectal Surgery
- Emergency Surgery
- Neurological Surgery
- Breast Surgery
- General Surgery
- Gastroenterological Surgery
- Ophthalmic Surgery
- Minimally Invasive Surgery
Abstract
Citation: Clin Surg. 2017;2(1):1662.Review Article | Open Access
Pancreatic Neuroendocrine Tumors in the 21st Century � An Update
R Kanthan, JL Senger, S Ahmed and SC Kanthan
Department of Pathology & Laboratory Medicine, University of Saskatchewan, Canada
Department of Surgery, University of Alberta, Canada
Division of Medical Oncology, University of Saskatchewan, Canada
Deparmtent of Surgery, University of Saskatchewan, Canada
*Correspondance to: Jenna-Lynn Senger
PDF Full Text DOI: 10.25107/2474-1647.1662
Abstract
Pancreatic Neuroendocrine Tumors (PNETs) are rare, reported to account for less than 1-2% of all pancreatic tumors. This, however, is likely an underestimation, as improved radiologic techniques and heightened awareness have resulted in an increase in the detection of incidentalomas, with estimations of true prevalence as high as 10%. The term “PNET” is an umbrella name encompasses a heterogenous group of neoplasms each with distinct clinical presentations, diagnostic radiographic features, management principles, and tumor/patient outcomes. In this context, accurate diagnosis is challenging, and management guidelines unclear. A high degree of clinical suspicion is required for best patient management. This manuscript provides a comprehensive of PNETs in the 21st century, in which we review the terminology, epidemiology classification, aetiopathogenesis, radiographic and histopathologic diagnostic features, management for localized and metastatic disease, as well as a review of features defining functional and non-functional PNETS, and finally describe prognostic features.
Keywords
Pancreatic neuroendocrine tumor; Insulinoma; Gastrinomas
Cite the article
Kanthan R, Senger JL, Ahmed S, Kanthan SC. Pancreatic Neuroendocrine Tumors in the 21st Century � An Update. Clin Surg. 2017; 2: 1662.