
Major Scope
- Colon and Rectal Surgery
- General Surgery
- Gynecologic Oncology
- Plastic Surgery
- Neurological Surgery
- Orthopaedic Surgery
- Orthopaedic Surgery of the Spine
- Neonatal Surgery
- Prenatal Surgery
- Trauma Surgery
- Surgical Intensivists, Specializing In Critical Care Patients
- Thoracic Surgery
- Congenital Cardiac Surgery
- Thoracic Surgery-Integrated
- Vascular Surgery
Abstract
Citation: Clin Surg. 2017;2(1):1527.Research Article | Open Access
To Evaluate the Efficacy of Non-Cultured Epidermal Cell Suspension in Cases of Stable Vitiligo
Leelavathy B, Akshi Bansal and Shilpa K
Department of Dermatology, Venereology and Leprosy, Bangalore Medical College and Research Institute, India
*Correspondance to: Leelavathy B
PDF Full Text DOI: 10.25107/2474-1647.1527
Abstract
Introduction: Vitiligo is an acquired disorder of pigmentation caused by loss of epidermal melanocytes. Surgery in vitiligo has come up a long way from tissue grafting to cellular grafting techniques which includes non-culture epidermal cell suspension.Materials and
Methods: 30 patients with vitiligo, stable for atleast 1 year were included in this study. Ultra-thin split thickness graft was harvested and incubated in Trypsin-EDTA. The suspension was centrifuged to obtain a pellet which was re-suspended and applied to derma braded recipient area.Results: Overall, 19 (66.67%) patients showed excellent (>90%) pigmentation, 5 (16.67%) had very well (50%- 75%) repigmentation and 4 patients (13.33%) had a good response (25%-50%). Majority of patients (53.33%) had good colour match with surrounding skin. 13 patients (43.33%) complained of dyspigmentation and 1(3.33%) patient had scarring at donor site.Conclusion: Non-cultured epidermal cell suspension is a safe and effective surgical modality in management of stable vitiligo.
Keywords
Cite the article
Leelavathy B, Bansal A, Shilpa K. To Evaluate the Efficacy of Non-Cultured Epidermal Cell Suspension in Cases of Stable Vitiligo. Clin Surg. 2017; 2: 1527.
Journal Basic Info
- Impact Factor: 2.395**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
- NLM ID: 101702548