To Evaluate the Efficacy of Non-Cultured Epidermal Cell Suspension in Cases of Stable Vitiligo

Leelavathy B, Akshi Bansal and Shilpa K

Department of Dermatology, Venereology and Leprosy, Bangalore Medical College and Research Institute, India

^*Correspondance to: Leelavathy B 

 PDF  Full Text DOI: 10.25107/2474-1647.1527

Abstract

Introduction: Vitiligo is an acquired disorder of pigmentation caused by loss of epidermal melanocytes. Surgery in vitiligo has come up a long way from tissue grafting to cellular grafting techniques which includes non-culture epidermal cell suspension.Materials and
Methods: 30 patients with vitiligo, stable for atleast 1 year were included in this study. Ultra-thin split thickness graft was harvested and incubated in Trypsin-EDTA. The suspension was centrifuged to obtain a pellet which was re-suspended and applied to derma braded recipient area.Results: Overall, 19 (66.67%) patients showed excellent (>90%) pigmentation, 5 (16.67%) had very well (50%- 75%) repigmentation and 4 patients (13.33%) had a good response (25%-50%). Majority of patients (53.33%) had good colour match with surrounding skin. 13 patients (43.33%) complained of dyspigmentation and 1(3.33%) patient had scarring at donor site.Conclusion: Non-cultured epidermal cell suspension is a safe and effective surgical modality in management of stable vitiligo.

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Cite the article

Leelavathy B, Bansal A, Shilpa K. To Evaluate the Efficacy of Non-Cultured Epidermal Cell Suspension in Cases of Stable Vitiligo. Clin Surg. 2017; 2: 1527.