Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Emergency Surgery
  •  Colon and Rectal Surgery
  •  General Surgery
  •  Endocrine Surgery
  •  Urology
  •  Robotic Surgery
  •  Ophthalmic Surgery
  •  Gastroenterological Surgery


Citation: Clin Surg. 2017;2(1):1423.Case Report | Open Access

Case Report: A Nodule on the Scalp with Exogenous Pigment

Nallayici EG, Kroft, Hogenes and Schreurs

Department of Surgery, Ziekenhuisgroep Twente (ZGT), Almelo, Netherlands
Department of Dermatology, Ziekenhuisgroep Twente (ZGT), Almelo, Netherlands
Department of Pathology, Laboratorium Pathologie Oost-Nederland (LABPON), Hengelo, Netherlands

*Correspondance to: Erol Gokhan Nallayici 

 PDF  Full Text DOI: 10.25107/2474-1647.1423


Background: Modifying hair colour is a common fashion statement in the modern society. Allergy and/or contact dermatitis on p-Phenylenediamine (PPD) and possible carcinogenetic effects of hair colouringare described side effects of hair colour dye, but longstanding cutaneous deposition of the dye pigment has never been described before in current literature.Observation: We present a 41-year-old Caucasian woman who was referred to our department of surgery with a nodule on her scalp. The nodule was slowly growing and was first noticed a couple of months ago. The nodule gave her cosmetic problems. She had no history of scalp trauma, dermal tattoos, infection or previous skin problems and no family history for dermal malignancies. With physical examination an elastic bluish nodule of 10 mm, without an opening in the centre was seen. The nodule was excised and histological analyses demonstrated an extensive granulomatous inflammatory reaction. These granulomas were associated with an excessive deposition of intracellular blue-black pigment of exogenously origin and double breaking foreign body materials.
Conclusion: Recurrent use of hair colour dye may induce pigment deposition in rare cases.


Exogenous pigment; Blue-black pigment; Nodule; Hair coloring; Hair dye

Cite the article

Nallayici EG, Kroft, Hogenes, Schreurs. Case Report: A Nodule on the Scalp with Exogenous Pigment. Clin Surg. 2017; 2: 1423.

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