Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Orthopaedic Surgery
  •  Transplant Surgery
  •  Colon and Rectal Surgery
  •  Gastroenterological Surgery
  •  Ophthalmic Surgery
  •  Emergency Surgery
  •  General Surgery
  •  Minimally Invasive Surgery


Citation: Clin Surg. 2017;2(1):1421.Research Article | Open Access

Study of the Effect of Ankaferd Blood Stopper on Outcome of Total Thyroidectomy

Aly Saber, Emad K Bayumi and Leonie Sophia van den Hoek

Department of Surgery, Port-Fouad General Hospital, Egypt
Department of General Surgery, Medical Academy Named after S.I. Georgiesky of Crimea Federal University, Russia
Department of Health Psychology, Liberty International University, USA

*Correspondance to: Aly Saber 

 PDF  Full Text DOI: 10.25107/2474-1647.1421


Introduction: During thyroidectomy, bleeding may obscure the operative field making safe dissection of recurrent laryngeal nerve and parathyroid gland difficult and prolonging the operation time. Ankaferd Blood Stopper (ABS) is a novel topical hemostatic agent of plant origin. The hemostatic mechanism of ABS involves the formation of an encapsulated protein network representing focal points for vital erythrocyte aggregation. The aim of this study was to compare the effectiveness of ABS as a local hemostatic agent for control thyroid bed bleeding after total thyroidectomy for benign thyroid diseases versus hemostasis achieved by conventional electrocauterization.Patients and
Methods: A total of 200 patients were subjected to primary total thyroidectomy for bilateral multinodular goitre due to compression symptoms or cosmetic purposes without previous neck surgery or radiotherapy. Our patients were divided into two main groups Ankaferd (group A) and Suture-Ligation (group B).Outcome Parameters: The following parameters were measured to compare the effect of ankaferd blood stopper versus conventional suture-ligation technique in decreasing the operative blood loss, operative time, securing laryngeal nerves and parathyroids, postoperative drainage and postoperative wound infection.
Results: Regarding the demographic data of our patients, there was no statistical difference between the two groups regarding age, sex and body mass index and also there was neither operative mortality nor 30 day death. In the ankaferd-treated group, mean operative time, mean intraoperative bleeding and postoperative drainage volumes were all reduced when compared with conventional suture-tie technique.Conclusion: In thyroid surgery like any other surgical interference, meticulous dissection with secured hemostasis are the most important steps to prevent intraoperative and postoperative bleeding. Ankaferd blood stopper seems effective in reducing both operative bleeding and postoperative drainage volumes when compared with the conventional suture and tie maneuver. Regarding its safety, ankaferd causes neither a foreign body reaction nor thrombocyte activation and actually allows the regeneration process to be completed with minimal signs of inflammation.


Total thyroidectomy; Multinodular goiter; Ankaferd

Cite the article

Saber A, Bayumi EK, van den Hoek LS. Study of the Effect of Ankaferd Blood Stopper on Outcome of Total Thyroidectomy. Clin Surg. 2017; 2: 1421.

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