Guillain-Barre Syndrome Following PCV Vaccine

Nidhi Ravishankar

Department of Internal Medicine, Windsor University School of Medicine, USA

^*Correspondance to: Nidhi Ravishankar 

 PDF  Full Text DOI: 10.25107/2474-1647.1413

Abstract

Guillain-Barre syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system attacking the peripheral nervous system. Although the causes still remain elusive, many studies in the past have linked GBS to vaccinations, such as influenza, but pneumococcal vaccine remains to be studied. This case report highlights a woman who developed bilateral lower extremity weakness from Guillain-Barre a month after administration of the PCV vaccine and subsequent respiratory failure. Possible etiology could be linked to the T-dependent stimulation response of GBS to the G1-specific B cells found in the peripheral blood. Full recovery is often rare in the syndrome, but rapid administration of IV Ig and extensive therapy has proved to show a good long-term outcome.

Keywords

Guillain-Barre syndrome; PCV vaccine; Peripheral nervous system

Cite the article

Ravishankar N. Guillain-Barre Syndrome Following PCV Vaccine. Clin Surg. 2017; 2: 1413.