Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Breast Surgery
  •  Cardiovascular Surgery
  •  Obstetrics Surgery
  •  Robotic Surgery
  •  Surgical Oncology
  •  Neurological Surgery
  •  Minimally Invasive Surgery
  •  General Surgery


Citation: Clin Surg. 2017;2(1):1329.Case Report | Open Access

Type a Aortic Dissection and Impaired Systolic Function in a Child with Loeys-Dietz Syndrome

Yan Li, Qian Chang, Xiangyang Qian, Xiaogang Sun and Mingyao Luo

Department of Cardiovascular Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, China

*Correspondance to: Yan Li 

 PDF  Full Text DOI: 10.25107/2474-1647.1329


Loeys-Dietz syndrome (LDS) is a recently recognized genetic aortic aneurysm syndrome characterized by the triad of hypertelorism, bifid uvula or cleft palate, and generalized arterial tortuosity with aneurysms and dissections throughout the arterial tree with a high risk of earlyonset aortic dissection but with no known myocardial involvement [1]. We report a child who was diagnosed as acute type A aortic dissection, a novel transforming growth factor beta (TGFβ) receptor type I (TGFBR1) mutation, and impaired systolic function after urgent surgical repair.


LDS: Loeys-dietz Syndrome; TGFβ: Transforming Growth Factor β; TGFBR1: TGF Beta-receptor Type I; LVEF: Left Ventricular Ejection Fraction

Cite the article

Li Y, Chang Q, Qian X, Sun X, Luo M. Type a Aortic Dissection and Impaired Systolic Function in a Child with Loeys- Dietz Syndrome. Clin Surg. 2017; 2: 1329.

Search Our Journal

Journal Indexed In

Articles in PubMed

Sildenafil Transiently Delays Early Alveolar Bone Healing of Tooth Extraction Sockets
 PubMed  PMC  PDF  Full Text
Antimicrobial Peptides: A Potential Therapeutic Option for Surgical Site Infections
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Use of Accessible Blood Filter for Postoperative Cell Salvage in Cardiac Surgery
 Abstract  PDF  Full Text
Laparoscopic Versus Robot Techniques for the Choledochal Cyst in Children: An Initial Meta-Analysis
 Abstract  PDF  Full Text
View More...