Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Bariatric Surgery
  •  Endocrine Surgery
  •  Gynecological Surgery
  •  Gastroenterological Surgery
  •  Emergency Surgery
  •  Robotic Surgery
  •  Cardiovascular Surgery
  •  Urology


Citation: Clin Surg. 2017;2(1):1308.Review Article | Open Access

Photodynamic Therapy as a Treatment to Nasopharyngeal Carcinoma

WU Wing Kei Ricky, CHU SM Ellie and Yow MN Christine

Department of Medical and Health Sciences, Tung Wah College, China
Department of Laboratory Sciences, Hong Kong Polytechnic University, China

*Correspondance to: WU Wing Kei Ricky 

 PDF  Full Text DOI: 10.25107/2474-1647.1308


NPC is highly prevalent in Hong Kong with more than 800 new cases reported annually. The epidemiologic evidence implies that Epstein-Barr virus (EBV) infection, environmental factors and genetic factors play roles in the tumorigenesis of NPC. Conventional treatment of NPC is chemoradiotherapy, yet the treatment outcomes in patients with advanced stage of NPC are unsatisfactory. Therefore development of new treatment strategies is crucial for patients with Nasopharyngeal Carcinoma (NPC), particularly for patients with drug resistance properties or distance recurrence. Photodynamic therapy (PDT) is an FDA approved cancer regimen which employs a combination of light-activated photosensitiser visible light and molecular oxygen to selectively destroy the biological targets. 3rd generation of photosensitizers with light activation by advance light sources such as coherent light source (laser) and non-coherent light source (LED) could be one of novel strategies in for NPC patients. In-depth investigation for selected PSs mediated PDT on NPC model is still underway.


Photodynamic therapy; Nasopharyngeal carcinoma; Epstein barr virus; Microrna; Drug resistance

Cite the article

WU Wing Kei Ricky, CHU SM Ellie, Yow MN Christine. Photodynamic Therapy as a Treatment to Nasopharyngeal Carcinoma. Clin Surg. 2017; 2: 1308.

Search Our Journal

Journal Indexed In

Articles in PubMed

Voice Outcomes in Laryngotracheal Stenosis: Impact of the Montgomery T-tube
 PubMed  PMC  PDF  Full Text
Risk Factors for Visual Impairment in an Uninsured Population and the Impact of the Affordable Care Act
 PubMed  PMC  PDF  Full Text
View More...

Articles with Grants

Is Epithelioid Hemangioendothelioma a Cold Tumor for Immune Check Point Inhibitors? A Case Report
 Abstract  PDF  Full Text
Massive Preperitoneal Hematoma after Open Hernia Repair with UltraPro Hernia System
 Abstract  PDF  Full Text
View More...