Major Scope

  •  Colon and Rectal Surgery
  •  General Surgery
  •  Gynecologic Oncology
  •  Plastic Surgery
  •  Neurological Surgery
  •  Orthopaedic Surgery
  •  Orthopaedic Surgery of the Spine
  •  Neonatal Surgery
  •  Prenatal Surgery
  •  Trauma Surgery
  •  Surgical Intensivists, Specializing In Critical Care Patients
  •  Thoracic Surgery
  •  Congenital Cardiac Surgery
  •  Thoracic Surgery-Integrated
  •  Vascular Surgery

Abstract

Citation: Clin Surg. 2016;1(1):1148.Review Article | Open Access

Management of Overwhelming Postsplenectomy Infection Syndrome

Naoki Hashimoto

*Correspondance to: Naoki Hashimoto 

 PDF  Full Text DOI: 10.25107/2474-1647.1148

Abstract

Overwhelming postsplenectomy infection (OPSI) is a rare medical emergency, mainly caused by encapsulated bacteria, shortly progressing from a mild flulike syndrome to a fulminant, potentially fatal, sepsis. The risk of OPSI is higher in children and in patients with underlying benign or malignant hematological disorders. The identification of Howell-Jolly bodies on peripheral blood examination is an important clue to the diagnosis of asplenia or hyposplenia. Management of these patients includes a combination of immunization, antibiotics prophylaxis. Patient’s education about long-term risk of OPSI and physician’s awareness of a potentially lethal medical emergency are important factor for preventing and management of OPSI.

Keywords

OPSI; Howell-Jolly body; Encapsulated bacteria; Vaccines

Cite the article

Hashimoto N. Management of Overwhelming Postsplenectomy Infection Syndrome. Clin Surg. 2016; 1: 1148.

Journal Basic Info

  • Impact Factor: 2.395**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
  • NLM ID: 101702548

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