Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Ophthalmic Surgery
  •  Surgical Oncology
  •  Endocrine Surgery
  •  Bariatric Surgery
  •  Pediatric Surgery
  •  Plastic Surgery
  •  Urology
  •  Cardiovascular Surgery

Abstract

Citation: Clin Surg. 2016;1(1):1067.Research Article | Open Access

The Role of Prophylactic Lymph Node Dissection in Patients with Intrahepatic Cholangiocarcinoma

Satoh D, Matsukawa H, Araki H and Shiozaki S

Department of Gastroenterological Surgery, Hiroshima City Hiroshima Citizens Hospital, Japan

*Correspondance to: Daisuke Satoh 

 PDF  Full Text DOI: 10.25107/2474-1647.1067

Abstract

Purpose: We investigated the role of prophylactic lymph node dissection (LND) in patients with intrahepatic cholangiocarcinoma (ICC).Methods: A retrospective analysis was performed evaluating the impact on survival of prophylactic LND and preoperative risk factors for histological lymph node metastasis (LNM) in a cohort of 49 patients with ICC of the mass-forming type, who underwent curative resection between 1995 and 2013.Results: There were no differences in both disease-free survival (DFS) and overall survival (OS) between the patients without LND and the patients with LND who did not have LNM. Multivariate analysis revealed that serum CA19-9 level >150 U/mL and LN size >5 mm on preoperative computed tomography (CT) were the significant preoperative risk factors for LNM. None of the patients with LN size <5 mm on preoperative CT and serum CA19-9 level ≤150 U/mL had LNM.Conclusions: Prophylactic LND did not significantly improve DFS or OS in the present study. Regional LND could be omitted for patients with LN size <5 mm in preoperative CT and serum CA19-9 level ≤150 U/mL who are unlikely to have LNM.

Keywords

Intrahepatic cholangiocarcinoma; Prophylactic lymph node dissection; Lymph node size; Serum CA 19-9 level

Cite the article

Satoh D, Matsukawa H, Araki H, Shiozaki S. The Role of Prophylactic Lymph Node Dissection in Patients with Intrahepatic Cholangiocarcinoma. Clin Surg. 2016; 1: 1067.

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