Clin Surg | Volume 7, Issue 1 | Research Article | Open Access

Image-Guided Percutaneous Biopsy and Pathological Diagnosis in Atypical Imaging Features of Tuberculous Spondylitis

Ming Lu#, Wei Chen#, Zixiong Lei, Shuangwu Dai, Changhe Hou, Shaohua Du, Qinglin Jin and Haomiao Li*

Department of Musculoskeletal Oncology, Center for Orthopaedic Surgery, The Third Affiliated Hospital of Southern Medical University, China
#These authors contributed equally to this work

*Correspondance to: Haomiao Li 

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Abstract

Background: Atypical tuberculous spondylitis is difficult to distinguish from malignancy and other diseases, leading to misdiagnosis and inadequate treatment. The Purpose of this study was to better elucidate image-guided percutaneous biopsy in the diagnosis of atypical imaging features of tuberculous spondylitis. Methods: We review retrospectively 8 patients with atypical imaging features of tuberculous spondylitis diagnosed by image-guided percutaneous biopsy. Eight patients with diverse clinical symptoms and atypical imaging features of tuberculous spondylitis were diagnosed by imageguided percutaneous biopsy and imprinted cytology and histology, then, treated by anti-tuberculous medication with or without operation. The incidence of complications (intra- and postoperative), changes in neurological status at final follow-up, and clinical outcomes were evaluated. The neurologic function was evaluated according to the Frankel grading system. Clinical outcomes of the patients were evaluated by Visual Analogic Scale (VAS) scores for pain, imaging (X-ray, CT and MRI) and laboratory examination. Result: All the eight patients were diagnosed as tuberculous spondylitis by histological and cytological examination of specimens. All of them had anti-tuberculous medication treatment and six of them received operation. One patient suffered pleural effusion after debridement of the thoracic lesion. The mean follow-up period was 16.2 months (6 to 37 months). Decreased VAS scores and improved neurological function were observed in all patients. Solid fusion and osteogenic osteosclerosis were observed at the final follow-up and no recurrences were observed in all cases. Conclusion: Image guided biopsy and pathological analysis is helpful for early diagnosis of the atypical imaging features of tuberculous spondylitis.

Citation:

Lu M, Chen W, Lei Z, Dai S, Hou C, Du S, et al. Image-Guided Percutaneous Biopsy and Pathological Diagnosis in Atypical Imaging Features of Tuberculous Spondylitis. Clin Surg. 2022; 7: 3484..

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