Chen F1* and Wu G2
1Department of Neurology, Institute of Neurology, Ruijin Hospital/Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, China
2Department of Cardiology, The First Affiliated Hospital of Wenzhou Medical University, China
Atrial fibrillation is a common type of arrhythmia, which can lead to vascular embolism and ischemic stroke in patients. Nonvalvular Atrial Fibrillation (NVAF) is the main type of Atrial Fibrillation (AF), and thrombosis is mainly found in the left atrial appendage. Left atrial appendage closure can effectively reduce the risk of thrombosis in the left atrial appendage entering cerebral circulation. The effectiveness of left atrial appendage closure still needs to be confirmed by high-quality clinical studies. In addition, the occlusives should be upgraded to meet clinical needs. Preoperative and postoperative procedures of left atrial appendage closure still need to be improved. This article reviews the progress in the prevention of ischemic stroke in patients with Nonvalvular Atrial Fibrillation (NVAF) by left atrial appendage closure, and gives main points remain to be solved and discussed for LAAC applications.
Left atrial appendage occlusion; Atrial fibrillation; NVAF
Chen F, Wu G. Percutaneous Left Atrial Appendage Occlusion in the Prevention of Ischemic Stroke in Patients with Nonvalvular Atrial Fibrillation. Clin Surg. 2021; 6: 3227..