Yusuke Kono*, Masayuki Kasahara, Yoshihiko Iida, Tatsuhiko Tsujisawa and Nobuyuki Shoji
Department of Ophthalmology, Kitasato University School of Medicine, JapanFulltext PDF
Purpose: To evaluate ocular biometric changes after trabectome surgery. Design: Prospective non-randomized cohort study. Methods: We evaluated ocular biometric change in 97 eyes of 81 patients who underwent trabectome surgery at Kitasato University Hospital, involving 37 eyes of 32 patients who underwent trabectome surgery alone (Trab-alone) and 60 eyes of 49 patients who underwent trabectome surgery combined with cataract surgery (Trab-combined). Intraocular Pressure (IOP), Axial Length (AL), Anterior Chamber Depth (ACD), and mean keratometry (mean K) were compared with before and after the surgery. Moreover, comparison of the changes in AL (ΔAL) and IOP (ΔIOP) was done using correlation analysis for each group. IOL MasterTM (Carl Zeiss Meditec Inc.) was used for the biometric measurements. Result: Three months after surgery, IOP was reduced from 24.4 ± 7.1 to 15.7 ± 3.3 mmHg in the Trab-alone group, from 24.7 ± 6.4 to 15.0 ± 5.8 mmHg in the Trab-combined group (Wilcoxon signed-rank test; P<0.001, P<0.001, respectively). AL was reduced from 25.17 ± 2.16 to 25.12 ± 2.14 mm in the Trab-alone group, from 24.09 ± 1.31 to 23.95 ± 1.30 mm in the Trab-combined group (Wilcoxon signed-rank test; P<0.001, P<0.001, respectively). ACD in the Trab-alone group was decreased slightly from 4.16 ± 0.78 to 4.12 ± 0.80 mm, and in the Trab-combined group was increased 3.14 ± 0.39 to 4.63 ± 0.45 mm. Change of ACD was not significant in the trab-alone group, whereas, it was significant in the Trab-combined group (Wilcoxon signed-rank test; P=0.539 and P<0.001). Mean K in the Trab-alone group was increased slightly from 44.13 ± 1.68 D and 44.19 ± 1.80 D, and in the Trab-combined group 44.46 ± 1.63 to 44.55 ± 1.61 D. Change of mean K was not significant in both groups (Wilcoxon signed-rank test P=0.484 and P=0.202). A significant correlation was recognized between ΔIOP and ΔAL in Trab-alone and Trab-combined groups (Spearman’s rank correlation coefficient: R=0.577, P<0.001; R=0.402, P=0.002, respectively). Conclusion: Ocular biometric changes was shown after trabectome surgery, indicating that we should take notice of the change of postoperative refraction or the refractive error after trabectome surgery combined with cataract surgery in the case whose preoperative IOP was higher.
Glaucoma; Trabectome; Trabeculectomy; IOP; Axial length; Ocular biometry
Kono Y, Kasahara M, Iida Y, Tsujisawa T, Shoji N. Ocular Biometric Changes after Trabectome Surgery. Clin Surg. 2019; 4: 2634.