Clin Surg | Volume 4, Issue 1 | Research Article | Open Access

A Comparison of a Laparoscopic Kidney Transplantation Technique and an Open Approach in a Pig Model

Bulang He1*, Gabrielle C Musk2, Zi Qin Ng3, Lingjun Mou3, Helen Kershaw2, Mark Newman4, Rajalingam Sinniah5 and Jeffrey M Hamdorf AM1

1Department of Surgery, The University of Western Australia, Australia
2The University of Western Australia, Australia
3Department of Surgery, Sir Charles Gairdner Hospital, Australia
4Department of Surgery, Murdoch University, Australia
5Department of Histopathology, Fiona Stanley Health Campus, Australia

*Correspondance to: Bulang He 

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Abstract

Introduction: The expansion of laparoscopic surgery has emerged in the field of kidney transplantation as it confers multiple benefits. The aim of this study was to compare the outcomes of kidney transplantation by laparoscopic surgery versus open surgery in a pig model. Materials and Methods: Sixteen large white pigs were included in this study. Ten pigs underwent laparoscopic kidney transplantation (Lap Group) and 6 pigs had open kidney transplantation (Open Group). Cooling of the kidney graft was introduced during vessel anastomosis. The time for vessel anastomosis was recorded. The kidney graft temperature and body temperature were monitored. Blood samples and biopsy of kidney graft were taken for analysis of kidney function. Results: All surgeries were performed successfully. The time for renal artery anastomosis was longer in the Lap Group while the time for renal vein and ureter anastomosis was similar in both groups. The increase in kidney graft temperature was 3.6°C less in the Open Group than in the Lap Group. The creatinine level was similar at all time points and there was no difference in histopathology between two groups. Conclusion: The kidney transplantation by laparoscopic surgery is safe and feasible. The kidney graft function was comparable in two groups. The laparoscopic technique has revealed a possible consideration for application to human orthotopic kidney transplantation in the future.

Keywords:

Laparoscopy; Kidney graft; Kidney transplantation

Citation:

He B, Musk GC, Ng ZQ, Mou L, Kershaw H, Newman M, et al. A Comparison of a Laparoscopic Kidney Transplantation Technique and an Open Approach in a Pig Model. Clin Surg. 2019; 4: 2611.

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