Post-Operative Tromboembolism: New Therapeutical Prospectives

Intagliata E

Department of Surgery, University of Catania, Italy

^*Correspondance to: Intagliata E 

 PDF  Full Text DOI: 10.25107/2474-1647.2237

Abstract

Despite the application of the thromboembolic prophylaxis, a residual risk of thromboembolic events persists after surgery. The knowledge of hemocoagulation system and its alterations secondary to the surgical trauma can allow understanding the reason why the risk of venous thromboembolism persists despite prophylaxis. In the last years, interaction between hemocoagulation system and immune system has become increasingly a subject of study. Studies in the Literature confirmed that the hemocoagulative system is influenced and altered by both the surgical trauma and the post-operative activation of the immune system, thus worsening a pro-coagulant state. Understanding all these mechanisms helps developing new strategies to reduce even more the risk of thromboembolism, and moreover to accomplish a proper anti-platelet therapy in patients with high risk of cardiovascular events candidate to surgical treatment.

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Cite the article

Intagliata E. Post-Operative Tromboembolism: New Therapeutical Prospectives. Clin Surg. 2018; 3: 2237.