Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Bariatric Surgery
  •  Emergency Surgery
  •  Gynecological Surgery
  •  Obstetrics Surgery
  •  Vascular Surgery
  •  Thoracic Surgery
  •  Transplant Surgery
  •  Orthopaedic Surgery

Abstract

Citation: Clin Surg. 2018;3(1):2153.Research Article | Open Access

More than Twenty Years’ Experience with “Zero-Hour” Transplant Kidney Biopsy

Peter Szakaly, Karoly Kalmar-Nagy, Dora Praksch, Tibor Vas and Adam Varga

Department of Surgery, University of Pecs, Hungary
Deaparment of Internal Medicine and Nephrology Center, University of Pecs, Hungary

*Correspondance to: Peter Szakaly 

 PDF  Full Text DOI: 10.25107/2474-1647.2153

Abstract

“Zero-hour” biopsies of 968 transplant kidney have been performed since 1994. Donor kidneys were categorized into five groups based on the morphological findings in “zero-hour” biopsies. No morphological abnormalities were found in 40.5% of the cases. Arteriosclerosis was seen in 21.3% of donor kidneys. Acute tubular necrosis 27.8%, chronic tubulointerstitial nephritis 3.9% or glomerulonephritis 6.5% were detectable in the cases remained. Not significant differences were found in individual groups concerning basic disease, duration of supplementary kidney treatment prior to transplantation, mean age of recipients and HLA, B and DR mismatches. During the follow-up period (on the average 1764 days) 733 biopsies were performed. Side effect due to the performance of “zero-hour” biopsy was not observed. Massive haematuria resulting bladder tamponade occurred only once during re-biopsies. We found very worse early and long-time results at the chronic tubulointerstitial group. Arteriosclerosis in the transplant kidney is one of the alloantigen independent factors of the chronic allograft nephropathy. “Zero-hour” biopsies could be useful and safe tools to predict early graft function. Additionally, “zero-hour” biopsies help the histological interpretation of consecutive graft re-biopsies.

Keywords

“Zero-Hour” Biopsy; Kidney Transplantation; Chronic Allograft Nephropathy

Cite the article

Szakaly P, Kalmar-Nagy K, Praksch D, Vas T, Varga A. More than Twenty Years’ Experience with “Zero-Hour” Transplant Kidney Biopsy. Clin Surg. 2018; 3: 2153.

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